[HTML][HTML] Clinical trial design in the era of precision medicine

E Fountzilas, AM Tsimberidou, HH Vo, R Kurzrock - Genome medicine, 2022 - Springer
Recent rapid biotechnological breakthroughs have led to the identification of complex and
unique molecular features that drive malignancies. Precision medicine has exploited next …

Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma

AJ Grossberg, LC Chu, CR Deig… - CA: a cancer journal …, 2020 - Wiley Online Library
Despite tremendous gains in the molecular understanding of exocrine pancreatic cancer,
the prognosis for this disease remains very poor, largely because of delayed disease …

[HTML][HTML] The role of patient-reported outcome measures in the continuum of cancer clinical care: ESMO Clinical Practice Guideline

M Di Maio, E Basch, F Denis, LJ Fallowfield, PA Ganz… - Annals of …, 2022 - Elsevier
Highlights•This ESMO Guideline provides key recommendations on the role of PROMs
during the care of patients with cancer.•It covers the use of PROMs in patients with cancer …

Management of cancer cachexia: ASCO guideline

EJ Roeland, K Bohlke, VE Baracos, E Bruera… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE To provide evidence-based guidance on the clinical management of cancer
cachexia in adult patients with advanced cancer. METHODS A systematic review of the …

Epithelial ovarian cancer

S Lheureux, C Gourley, I Vergote, AM Oza - The Lancet, 2019 - thelancet.com
Epithelial ovarian cancer generally presents at an advanced stage and is the most common
cause of gynaecological cancer death. Treatment requires expert multidisciplinary care …

Real time remote symptom monitoring during chemotherapy for cancer: European multicentre randomised controlled trial (eSMART)

R Maguire, L McCann, G Kotronoulas, N Kearney… - Bmj, 2021 - bmj.com
Objective To evaluate effects of remote monitoring of adjuvant chemotherapy related side
effects via the Advanced Symptom Management System (ASyMS) on symptom burden …

Phase III randomized controlled trial of eRAPID: eHealth intervention during chemotherapy

K Absolom, L Warrington, E Hudson… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE Electronic patient self-Reporting of Adverse-events: Patient Information and
aDvice (eRAPID) is an online eHealth system for patients to self-report symptoms during …

Overall survival results of a trial assessing patient-reported outcomes for symptom monitoring during routine cancer treatment

E Basch, AM Deal, AC Dueck, HI Scher, MG Kris… - Jama, 2017 - jamanetwork.com
Methods| The study was approved by the Memorial Sloan Kettering institutional review
board and written informed consent was obtained from participants. Consecutive patients …

[HTML][HTML] Digital remote monitoring plus usual care versus usual care in patients treated with oral anticancer agents: the randomized phase 3 CAPRI trial

O Mir, M Ferrua, A Fourcade, D Mathivon… - Nature Medicine, 2022 - nature.com
Strategies that individualize the care of cancer patients receiving oral anticancer agents offer
opportunities to improve treatment adherence and patient care. However, the impact of …

[HTML][HTML] How do patient reported outcome measures (PROMs) support clinician-patient communication and patient care? A realist synthesis

J Greenhalgh, K Gooding, E Gibbons, S Dalkin… - Journal of patient …, 2018 - Springer
Background In this paper, we report the findings of a realist synthesis that aimed to
understand how and in what circumstances patient reported outcome measures (PROMs) …