Epithelial-to-mesenchymal transition (EMT) mechanism is responsible for metastasis and
migration of cancer cells to neighboring cells and tissues. Morphologically, epithelial cells …

One of the primary causes of attenuated or loss of efficacy of cancer chemotherapy is the
emergence of multidrug resistance (MDR). Numerous studies have been published …

Solid tumors often grow in a micro-environment characterized by< 2% O 2 tension. This
condition, together with the aberrant activation of specific oncogenic patwhays, increases …

Simple Summary Drug resistance is prevalent in many types of cancer and decreases
patient survival. The taxanes are anti-mitotic chemotherapeutic agents, widely used since …

There are several interactions within the tumor microenvironment (TME) that affect the
response of cancer cells to therapy. There are also a large number of cells and secretions in …

Hypoxia is a condition commonly observed in the core of solid tumors. The hypoxia-
inducible factors (HIF) act as hypoxia sensors that orchestrate a coordinated response …

Cancer is one of most the significant threats to human health worldwide, and the primary
method of treating solid tumours is surgery. Propofol, one of the most widely used …

Resveratrol (RES) is a naturally existing polyphenol which exhibits anti-oxidant, anti-
inflammatory, and anti-cancer properties. In recent years, RES has attracted attention for its …

Epithelial-mesenchymal transition (EMT) is a complicated molecular process that governs
cellular shape and function changes throughout tissue development and embryogenesis. In …

Non-small cell lung cancer (NSCLC) is associated with high morbidity and mortality.
Propofol functions as a tumor-inhibitor drug by regulating microRNAs (miRNAs). The primary …