Background: Pharmacist's direct intervention or participation in multidisciplinary
management teams can improve the clinical outcome and quality of life of patients. We …

Although enteral nutrition may provide some benefit as SUP, existing data are not strong
enough to validate their use in place of acid suppressive therapy. Clinicians should continue …

The gut microbiome is impacted by environmental exposures and has been implicated in
many physical and mental health conditions, including anxiety disorders, affective disorders …

Background The potentially inappropriate use of the proton pump inhibitors is prevalent in
older adults. Aim To evaluate the impact of a clinical pharmacist-led stewardship program for …

Purpose The economic impact of critical care pharmacists in the intensive care unit (ICU)
setting has not been evaluated in Singapore despite ICUs being high-cost areas. This study …

Annual prevalence estimates of peptic ulcer disease range between 0· 12% and 1· 5%.
Peptic ulcer disease is usually attributable to Helicobacter pylori infection, intake of some …

Purpose: Recent data highlight unclear efficacy and potential negative sequelae of stress
ulcer prophylaxis (SUP) in the intensive care unit (ICU). Minimizing SUP exposure has …

中重型颅脑损伤是复杂的危重临床疾病, 容易继发应激性溃疡(stress ulcer, SU) 值得关注.
中重型颅脑损伤继发应激性溃疡的机制复杂, 多与颅内压增高, 迷走神经兴奋 …

Background: X-ray and pH testing, which clinical practice guidelines have proven to be
effective in determining nasogastric tube (NGT) placement, were named the high-value …

Background Stress ulcers in patients with traumatic brain injury (TBI) and spinal cord injury
(SCI) present significant morbidity and mortality risks. Despite the low reported stress ulcer …