[HTML][HTML] Underlying anticancer mechanisms and synergistic combinations of phytochemicals with cancer chemotherapeutics: potential benefits and risks

M Ayaz, A Nawaz, S Ahmad, OF Mosa… - Journal of Food …, 2022 - hindawi.com
Cancer therapies are associated with various challenges including the emergence of
multidrug resistant tumors, toxicological issues, severe side effects, and economic burden …

[HTML][HTML] Anti-inflammatory effects of thymoquinone and its protective effects against several diseases

Z Kohandel, T Farkhondeh, M Aschner… - Biomedicine & …, 2021 - Elsevier
Abstract Thymoquinone (TQ, 2-methyl-5-isopropyl-1, 4-benzoquinone), a monoterpene
molecule present in Nigella sativa L., has an anti-inflammatory, anti-oxidant, and anti …

[HTML][HTML] Biological properties of ruthenium (II)/(III) complexes with flavonoids as ligands

M Małecka, A Skoczyńska, DM Goodman… - Coordination Chemistry …, 2021 - Elsevier
This review highlights the progress in the development of ruthenium (II)/(III) complexes with
flavone derivatives as potential therapeutic agents. We focused on natural hydroxyflavone …

In vitro toxicity of naringin and berberine alone, and encapsulated within PMMA nanoparticles

J Secerli, Ş Adatepe, S Altuntas, GR Topal, O Erdem… - Toxicology in Vitro, 2023 - Elsevier
Phytochemical compounds, such as naringin and berberine, have been used for many years
due to their antioxidant activities, and consequently, beneficial health effects. In this study, it …

Antiviral plant‐derived natural products to combat RNA viruses: Targets throughout the viral life cycle

L Owen, K Laird, M Shivkumar - Letters in Applied Microbiology, 2022 - academic.oup.com
There is a need for new effective antivirals, particularly in response to the development of
antiviral drug resistance and emerging RNA viruses such as SARS‐CoV‐2. Plants are a …

Liposomal nanoformulation as a carrier for curcumin and pEGCG—study on stability and anticancer potential

L Piwowarczyk, M Kucinska, S Tomczak… - Nanomaterials, 2022 - mdpi.com
Nanoformulations are regarded as a promising tool to enable the efficient delivery of active
pharmaceutical ingredients to the target site. One of the best-known and most studied …

Phytochemical components, antioxidant and anticancer activity of 18 major medicinal plants in Albaha region, Saudi Arabia

AA Alzandi, EA Taher, NA Al-Sagheer… - Biocatalysis and …, 2021 - Elsevier
Medicinal plants have a great role in influencing health all over the world. There are few
studies for the phytochemical investigations in medicinal plants were conducted in Saudi …

Phytochemical profiling and cytotoxic potential of Arnebia nobilis root extracts against hepatocellular carcinoma using in-vitro and in-silico approaches

A Kiran, A Altaf, M Sarwar, A Malik, T Maqbool, Q Ali - Scientific Reports, 2023 - nature.com
Hepatocellular carcinoma is the fifth most prevalent cancer worldwide. The emergence of
drug resistance and other adverse effects in available anticancer options are challenging to …

The anticancer activity of carbazole alkaloids

F Song, D Liu, X Huo, D Qiu - Archiv der Pharmazie, 2022 - Wiley Online Library
Chemotherapy is the first choice for the majority of cancers, but severe side effects and drug
resistance restrict the actual clinical efficacy. Carbazole alkaloids, mainly from the Rutaceae …

Compounds targeting ferroptosis in breast cancer: progress and their therapeutic potential

C Xu, Y Chen, Q Yu, J Song, Y Jin, X Gao - Frontiers in Pharmacology, 2023 - frontiersin.org
In recent years, there has been a significant increase in the incidence of Breast cancer (BC),
making it the most common cancer among women and a major threat to women's health …