Macrophage-targeted nanomedicine for the diagnosis and treatment of atherosclerosis
Nanotechnology could improve our understanding of the pathophysiology of atherosclerosis
and contribute to the development of novel diagnostic and therapeutic strategies to further …
and contribute to the development of novel diagnostic and therapeutic strategies to further …
[HTML][HTML] Protein-based nanoparticles as drug delivery systems
Nanoparticles have been extensively used as carriers for the delivery of chemicals and
biomolecular drugs, such as anticancer drugs and therapeutic proteins. Natural …
biomolecular drugs, such as anticancer drugs and therapeutic proteins. Natural …
Apolipoproteins in vascular biology and atherosclerotic disease
A Mehta, MD Shapiro - Nature Reviews Cardiology, 2022 - nature.com
Apolipoproteins are important structural components of plasma lipoproteins that influence
vascular biology and atherosclerotic disease pathophysiology by regulating lipoprotein …
vascular biology and atherosclerotic disease pathophysiology by regulating lipoprotein …
High-density lipoprotein revisited: biological functions and clinical relevance
A von Eckardstein, BG Nordestgaard… - European heart …, 2023 - academic.oup.com
Previous interest in high-density lipoproteins (HDLs) focused on their possible protective
role in atherosclerotic cardiovascular disease (ASCVD). Evidence from genetic studies and …
role in atherosclerotic cardiovascular disease (ASCVD). Evidence from genetic studies and …
HDL and reverse cholesterol transport: Basic mechanisms and their roles in vascular health and disease
Cardiovascular disease, with atherosclerosis as the major underlying factor, remains the
leading cause of death worldwide. It is well established that cholesterol ester-enriched foam …
leading cause of death worldwide. It is well established that cholesterol ester-enriched foam …
Atualização da diretriz brasileira de dislipidemias e prevenção da aterosclerose–2017
AA Faludi, MCO Izar, JFK Saraiva… - Arquivos brasileiros de …, 2017 - SciELO Brasil
Material de distribuição exclusiva à classe médica. Os Arquivos Brasileiros de Cardiologia
não se responsabilizam pelo acesso indevido a seu conteúdo e que contrarie a …
não se responsabilizam pelo acesso indevido a seu conteúdo e que contrarie a …
Effect of evolocumab on progression of coronary disease in statin-treated patients: the GLAGOV randomized clinical trial
Importance Reducing levels of low-density lipoprotein cholesterol (LDL-C) with intensive
statin therapy reduces progression of coronary atherosclerosis in proportion to achieved …
statin therapy reduces progression of coronary atherosclerosis in proportion to achieved …
Combating physical inactivity during the COVID-19 pandemic
Physical inactivity is common during periods of self-isolation, but for patients with rheumatic
diseases, there are crucial benefits to be gained from maintaining an active lifestyle …
diseases, there are crucial benefits to be gained from maintaining an active lifestyle …
Coronary Atherosclerotic Plaque Regression: JACC State-of-the-Art Review
LP Dawson, M Lum, N Nerleker, SJ Nicholls… - Journal of the American …, 2022 - jacc.org
Over the last 3 decades there have been substantial improvements in treatments aimed at
reducing cardiovascular (CV) events. As these treatments have been developed, there have …
reducing cardiovascular (CV) events. As these treatments have been developed, there have …
Cholesterol, inflammation and innate immunity
AR Tall, L Yvan-Charvet - Nature Reviews Immunology, 2015 - nature.com
Hypercholesterolaemia leads to cholesterol accumulation in macrophages and other
immune cells, which promotes inflammatory responses, including augmentation of Toll-like …
immune cells, which promotes inflammatory responses, including augmentation of Toll-like …