Septins are an integral component of the cytoskeleton, assembling into higher-order
oligomers and filamentous polymers that associate with actin filaments, microtubules and …

Septins belong to a family of proteins that is highly conserved in eukaryotes and is
increasingly recognized as a novel component of the cytoskeleton. All septins are GTP …

The recent rapid accumulation of knowledge on the dynamics and structure of the plasma
membrane has prompted major modifications of the textbook fluid-mosaic model. However …

Cells change shape in response to diverse environmental and developmental conditions,
creating topologies with micron-scale features. Although individual proteins can sense …

Many aspects of cytoskeletal assembly and dynamics can be recapitulated in vitro; yet, how
the cytoskeleton integrates signals in vivo across cellular membranes is far less understood …

Septins are a conserved family of GTP-binding proteins that assemble into symmetric linear
heterooligomeric complexes, which in turn are able to polymerize into apolar filaments and …

The structural plasticity of dendritic spines is considered to be essential for various forms of
synaptic plasticity, learning, and memory. The process is mediated by a complex signaling …

Septins comprise a conserved family of proteins that are found primarily in fungi and
animals. These GTP-binding proteins have several roles during cell division, cytoskeletal …

The small size of dendritic spines belies the elaborate role they play in excitatory synaptic
transmission and ultimately complex behaviors. The cytoskeletal architecture of the spine is …

Activity-regulated gene expression is believed to play a key role in the development and
refinement of neuronal circuitry. Nevertheless, the transcriptional networks that regulate …