[HTML][HTML] Acute kidney injury: definition, pathophysiology and clinical phenotypes
K Makris, L Spanou - The clinical biochemist reviews, 2016 - ncbi.nlm.nih.gov
Acute kidney injury (AKI) is a clinical syndrome that complicates the course and worsens the
outcome in a significant number of hospitalised patients. Recent advances in clinical and …
outcome in a significant number of hospitalised patients. Recent advances in clinical and …
[HTML][HTML] Reducing major risk factors for chronic kidney disease
VA Luyckx, KR Tuttle, G Garcia-Garcia… - Kidney international …, 2017 - Elsevier
Chronic kidney disease (CKD) is a global public health concern and a key determinant of
poor health outcomes. While the burden of CKD is reasonably well defined in developed …
poor health outcomes. While the burden of CKD is reasonably well defined in developed …
Long-term risk of coronary events after AKI
VC Wu, CH Wu, TM Huang, CY Wang… - Journal of the …, 2014 - journals.lww.com
The incidence rate of AKI in hospitalized patients is increasing. However, relatively little
attention has been paid to the association of AKI with long-term risk of adverse coronary …
attention has been paid to the association of AKI with long-term risk of adverse coronary …
Exendin-4 and sitagliptin protect kidney from ischemia-reperfusion injury through suppressing oxidative stress and inflammatory reaction
YT Chen, TH Tsai, CC Yang, CK Sun, LT Chang… - Journal of translational …, 2013 - Springer
Background This study tested the hypothesis that exendin-4 and sitagliptin can effectively
protect kidney from acute ischemia-reperfusion (IR) injury. Methods Adult SD-rats (n= 48) …
protect kidney from acute ischemia-reperfusion (IR) injury. Methods Adult SD-rats (n= 48) …
[HTML][HTML] SIRT1 is a key regulatory target for the treatment of the endoplasmic reticulum stress-related organ damage
F Wang, S Yao, H Xia - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Endoplasmic reticulum (ER) stress is an evolutionarily conserved adaptive response that
contributes to deal with the misfolded or unfolded protein in the lumen of the ER and restore …
contributes to deal with the misfolded or unfolded protein in the lumen of the ER and restore …
Long-term remote organ consequences following acute kidney injury
Acute kidney injury (AKI) has been a global health epidemic problem with soaring incidence,
increased long-term risks for multiple comorbidities and mortality, as well as elevated …
increased long-term risks for multiple comorbidities and mortality, as well as elevated …
Inhibition of the SIRT1 signaling pathway exacerbates endoplasmic reticulum stress induced by renal ischemia/reperfusion injury in type 1 diabetic rats
J Zhang, L Wang, D Gong… - Molecular …, 2020 - spandidos-publications.com
The aim of the present study was to investigate whether the diabetic kidney is more
susceptible to ischemia/reperfusion (I/R) injury, and identify the potential mechanisms …
susceptible to ischemia/reperfusion (I/R) injury, and identify the potential mechanisms …
The daily burden of acute kidney injury: a survey of US nephrologists on World Kidney Day
JL Koyner, J Cerdá, SL Goldstein, BL Jaber… - American journal of …, 2014 - Elsevier
Background World Kidney Day 2013 focused on raising awareness of the impact and
consequences of acute kidney injury (AKI). Although many studies have examined rates of …
consequences of acute kidney injury (AKI). Although many studies have examined rates of …
Roxadustat (FG‐4592) protects against ischaemia/reperfusion‐induced acute kidney injury through inhibiting the mitochondrial damage pathway in mice
M Zhang, R Dong, J Yuan, J Da… - Clinical and …, 2022 - Wiley Online Library
Abstract Ischaemia–reperfusion (I/R) is one of the main factors of acute kidney injury (AKI).
mitochondrial damage pathway are important features of I/R induced‐acute kidney injury …
mitochondrial damage pathway are important features of I/R induced‐acute kidney injury …
A nationwide survey of clinical characteristics, management, and outcomes of acute kidney injury (AKI)–patients with and without preexisting chronic kidney disease …
HC Pan, PC Wu, VC Wu, YF Yang, TM Huang… - Medicine, 2016 - journals.lww.com
Acute kidney injury (AKI) is a common complication in hospitalized patients. The
International Society of Nephrology implemented the “0 by 25” initiative aimed at preventing …
International Society of Nephrology implemented the “0 by 25” initiative aimed at preventing …