Emerging roles of oxyntomodulin-based glucagon-like peptide-1/glucagon co-agonist analogs in diabetes and obesity

Y Zhihong, W Chen, Z Qianqian, S Lidan, Z Qiang… - Peptides, 2023 - Elsevier
Oxyntomodulin (OXM) is an endogenous peptide hormone secreted from the intestines
following nutrient ingestion that activates both glucagon-like peptide-1 (GLP-1) and …

Enteroendocrine cells and gut hormones as potential targets in the crossroad of the gut-kidney axis communication

JAO Nery Neto, VY Yariwake, NOS Câmara… - Frontiers in …, 2023 - frontiersin.org
Recent studies suggest that disruptions in intestinal homeostasis, such as changes in gut
microbiota composition, infection, and inflammatory-related gut diseases, can be associated …

An Investigation of the Molecular Mechanisms Underlying the Analgesic Effect of Jakyak‐Gamcho Decoction: A Network Pharmacology Study

HS Lee, IH Lee, K Kang, SI Park… - Evidence‐Based …, 2020 - Wiley Online Library
Herbal drugs have drawn substantial interest as effective analgesic agents; however, their
therapeutic mechanisms remain to be fully understood. To address this question, we …

Isoquercitrin attenuates neuroinflammation in LPS-stimulated BV2 microglia cells via p38MAPK/NF-κB pathway

S Chang, Y Chang, J Wang, X Huang - Turkish Journal of …, 2024 - degruyter.com
Objectives Microglia mediated neuronal inflammation has been reported to be responsible
for neurodegenerative disease. Isoquercitrin (IQC), widely found in fruits, vegetables and …

Fargesin promotes LPS-alleviated microglial M2 polarization and relieves neuropathic pain.

C Wu, L Zhou, L Wang, L Liu - Signa Vitae, 2024 - search.ebscohost.com
Neuropathic pain is chronic pain that disrupts a patient's normal life and causes enormous
suffering. Fargesin (Far), a product derived from Mulan, has been discovered to exhibit …

Tumor Necrosis Factor-Alpha and the Chronification of Acute Pain

DI Smith, H Tran - Pathogenesis of Neuropathic Pain: Diagnosis and …, 2022 - Springer
The role of TNF-α in the chronification of acute encompasses a number of mechanisms. It is
expressed following a neuronal injury and can form its own ion channel in a three-step …