Exosomes─ nature's lipid nanoparticles, a rising star in drug delivery and diagnostics

R Tenchov, JM Sasso, X Wang, WS Liaw, CA Chen… - ACS …, 2022 - ACS Publications
Exosomes are a subgroup of nanosized extracellular vesicles enclosed by a lipid bilayer
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …

Hybrid exosomes, exosome-like nanovesicles and engineered exosomes for therapeutic applications

J Mondal, S Pillarisetti, V Junnuthula, M Saha… - Journal of Controlled …, 2023 - Elsevier
Exosomes are endosome-derived nanovesicles involved in cellular communication. They
are natural nanocarriers secreted by various cells, making them suitable candidates for …

Exosome engineering in cell therapy and drug delivery

S Sadeghi, FR Tehrani, S Tahmasebi, A Shafiee… - …, 2023 - Springer
Cell-derived exosomes have opened new horizons in modern therapy for advanced drug
delivery and therapeutic applications, due to their key features such as low immunogenicity …

Exosomal proteins and lipids as potential biomarkers for lung cancer diagnosis, prognosis, and treatment

MT Hsu, YK Wang, YJ Tseng - Cancers, 2022 - mdpi.com
Simple Summary Exosomes (or extracellular vesicles) are known to mediate intercellular
communication and to transmit molecular signals between cells. Molecules carried by …

Biogenesis, isolation, and detection of exosomes and their potential in therapeutics and Diagnostics

S Sonbhadra, Mehak, LM Pandey - Biosensors, 2023 - mdpi.com
The increasing research and rapid developments in the field of exosomes provide insights
into their role and significance in human health. Exosomes derived from various sources …

The emerging roles of long non-coding RNA in host immune response and intracellular bacterial infections

A Arunima, EJ van Schaik, JE Samuel - Frontiers in cellular and …, 2023 - frontiersin.org
The long non-coding RNAs (lncRNAs) are evolutionarily conserved classes of non-coding
regulatory transcripts of> 200 nucleotides in length. They modulate several transcriptional …

Discerning the prospects of miRNAs as a multi-target therapeutic and diagnostic for alzheimer's disease

D Bhatnagar, S Ladhe, D Kumar - Molecular Neurobiology, 2023 - Springer
Although over the last few decades, numerous attempts have been made to halt Alzheimer's
disease (AD) progression and mitigate its symptoms, only a few have been proven …

Exosomes in brain diseases: Pathogenesis and therapeutic targets

Q Si, L Wu, D Pang, P Jiang - MedComm, 2023 - Wiley Online Library
Exosomes are extracellular vesicles with diameters of about 100 nm that are naturally
secreted by cells into body fluids. They are derived from endosomes and are wrapped in …

[HTML][HTML] Exosomes and ultrasound: the future of theranostic applications

B Sridharan, HG Lim - Materials Today Bio, 2023 - Elsevier
Biomaterials and pertaining formulations have been very successful in various diagnostic
and therapeutic applications because of its ability to overcome pharmacological limitations …

Exosomes: potential player in endothelial dysfunction in cardiovascular disease

F Nikdoust, M Pazoki, M Mohammadtaghizadeh… - Cardiovascular …, 2021 - Springer
Exosomes are spherical bilayer membrane vesicles with an average diameter of 40–100
nm. These particles perform a wide range of biological activities due to their contents …