[HTML][HTML] Physioxia has a beneficial effect on cartilage matrix production in interleukin-1 beta-inhibited mesenchymal stem cell chondrogenesis

G Pattappa, R Schewior, I Hofmeister, J Seja, J Zellner… - Cells, 2019 - mdpi.com
Osteoarthritis (OA) is a degenerative condition that involves the production of inflammatory
cytokines (eg, interleukin-1β (IL-1β), tumour necrosis factor-alpha (TNF-α) and interleukin-6 …

[HTML][HTML] Combinatorial physicochemical stimuli in the three-dimensional environment of a hyaluronic acid hydrogel amplify chondrogenesis by stimulating …

J Ahn, Y Arai, BJ Kim, YK Seo, JJ Moon, DA Shin… - NPG Asia …, 2022 - nature.com
The chondrogenesis of stem cells and cartilage tissue regeneration are more efficient in a
three-dimensional (3D) environment than in a two-dimensional (2D) environment. Although …

[HTML][HTML] Low-intensity pulsed ultrasound promotes Schwann cell viability and proliferation via the GSK-3β/β-catenin signaling pathway

C Ren, X Chen, N Du, S Geng, Y Hu, X Liu… - … journal of biological …, 2018 - ncbi.nlm.nih.gov
Background: It has been reported that ultrasound enhances peripheral nerve regeneration,
but the mechanism remains elusive. Low-intensity pulsed ultrasound (LIPUS) has been …

[HTML][HTML] Effects of low-level laser therapy and therapeutic ultrasound on Freund's complete adjuvant-induced knee arthritis model in rats

S Okur, Z Okumuş - Archives of Rheumatology, 2023 - ncbi.nlm.nih.gov
Objectives The aim of this study was to evaluate and monitor the effect of low-level laser
therapy (LLLT) and therapeutic ultrasound (TU) alone, or combined with intra-articular …

Low-intensity pulsed ultrasound promotes cell motility through vinculin-controlled Rac1 GTPase activity

P Atherton, F Lausecker, A Harrison… - Journal of Cell …, 2017 - journals.biologists.com
Low-intensity pulsed ultrasound (LIPUS) is a therapy used clinically to promote healing.
Using live-cell imaging we show that LIPUS stimulation, acting through integrin-mediated …

Effects of low-intensity pulsed ultrasound on knee osteoarthritis: A systematic review and meta-analysis of randomized controlled trials

H Chen, Z Wang, X Zhang, M Sun - Clinical Rehabilitation, 2022 - journals.sagepub.com
Objective To systemically review the effects of low-intensity pulsed ultrasound (LIPUS) on
pain relief and functional recovery in patients with knee osteoarthritis (KOA). Data sources …

[HTML][HTML] Ghrelin prevents articular cartilage matrix destruction in human chondrocytes

L Cao, X Gao, Z Chen, S Guo, Z He, Y Qian… - Biomedicine & …, 2018 - Elsevier
Osteoarthritis (OA) is the most common form of arthritis worldwide. Excessive production of
pro-inflammatory cytokines such as interleukin-1β (IL-1β) plays a key role in the …

Ultrasound Tissue Engineering Technology for Regulating Immune Microenvironment

X Li, X Ding, Y He, W Yi, Y Zhu, W Han… - Advanced Functional …, 2024 - Wiley Online Library
The immune microenvironment is critical for the occurrence, progression, and treatment of
diseases. Ultrasound tissue engineering technology utilizes ultrasound and the principles of …

[HTML][HTML] LIPUS regulates the progression of knee osteoarthritis in mice through primary cilia-mediated TRPV4 channels

S Wu, H Zhou, H Ling, Y Sun, Z Luo, TN Ngo, Y Fu… - Apoptosis, 2024 - Springer
Osteoarthritis (OA) is a common disease in middle-aged and elderly people. An imbalance
in calcium ion homeostasis will contribute to chondrocyte apoptosis and ultimately lead to …

[HTML][HTML] Continuous low-intensity ultrasound attenuates IL-6 and TNFα-induced catabolic effects and repairs chondral fissures in bovine osteochondral explants

N Sahu, HJ Viljoen, A Subramanian - BMC musculoskeletal disorders, 2019 - Springer
Background Cartilage repair outcomes are compromised in a pro-inflammatory environment;
therefore, the mitigation of pro-inflammatory responses is beneficial. Treatment with …