Nanodrug Delivery Strategies to Signaling Pathways in Alopecia

X Wu, Y Du - Molecular Pharmaceutics, 2023 - ACS Publications
Over 50% of the global population suffers from hair loss. The mixed results in the treatment
of hair loss reveal the limitations of conventional commercial topical drugs. One the one …

[HTML][HTML] Efficacy and key materials of East Asian herbal medicine combined with conventional medicine on inflammatory skin lesion in patients with psoriasis vulgaris …

HG Jo, H Kim, E Baek, D Lee, JH Hwang - Pharmaceuticals, 2023 - mdpi.com
Psoriasis is a chronic inflammatory disease that places a great burden on both individuals
and society. The use of East Asian herbal medicine (EAHM) in combination with …

Critical review on anti‐inflammation effects of saponins and their molecular mechanisms

T Wijesekara, J Luo, B Xu - Phytotherapy Research, 2024 - Wiley Online Library
This review highlights the increasing interest in one of the natural compounds called
saponins, for their potential therapeutic applications in addressing inflammation which is a …

[HTML][HTML] Anti-Inflammatory and Antioxidant Activities of Lipophilic Fraction from Liriope platyphylla Seeds Using Network Pharmacology, Molecular Docking, and In …

VL Truong, YJ Bae, RHG Rarison, JH Bang… - International Journal of …, 2023 - mdpi.com
Antioxidant and anti-inflammatory mechanisms counteract the pathogenesis of chronic
diseases, such as diabetes, aging, and cancer. Therefore, enhancing antioxidant and anti …

Lipidomic analysis of facial skin surface lipids in acne in young women

Q Su, X Hu, M Yang, H He, Y Jia - International Journal of …, 2024 - Wiley Online Library
Background Alterations in the secretion and composition of skin surface lipids (SSL) are
closely associated with the development of acne. Lipidomics is a useful tool to analyse the …

Targeting PI3K/AKT/mTOR Signaling to Overcome Drug Resistance in Cancer

M Tufail, WD Wan, C Jiang, N Li - Chemico-Biological Interactions, 2024 - Elsevier
This review comprehensively explores the challenge of drug resistance in cancer by
focusing on the pivotal PI3K/AKT/mTOR pathway, elucidating its role in oncogenesis and …

[HTML][HTML] Pivotal Role of mTOR in Non-Skin Manifestations of Psoriasis

K Joo, C Karsulovic, M Sore, L Hojman - International Journal of …, 2024 - mdpi.com
Psoriasis is a chronic inflammatory condition affecting 2% of the Western population. It
includes diverse manifestations influenced by genetic predisposition, environmental factors …

[HTML][HTML] Dietary Polyphenols Effects on Focal Adhesion Plaques and Metalloproteinases in Cancer Invasiveness

R Carrano, M Grande, E Leti Maggio, C Zucca, R Bei… - Biomedicines, 2024 - mdpi.com
Focal adhesion plaques (FAPs) play an important role in the communication between cells
and the extracellular matrix (ECM) and in cells' migration. FAPs are macromolecular …

Single-Cell RNA Sequencing Identifies WARS1+ Mesenchymal Stem Cells with Enhanced Immunomodulatory Capacity and Improved Therapeutic Efficacy

X Li, F Zhang, L Sun, X Cai, F Lou, Y Sun… - The Journal of …, 2024 - journals.aai.org
Psoriasis is a common inflammatory skin disorder with no cure. Mesenchymal stem cells
(MSCs) have immunomodulatory properties for psoriasis, but the therapeutic efficacies …

Comparative proteomics reveal the humoral immune rejection of pearl oyster Pinctada fucata to xenograft from Pinctada maxima

P Wang, Y Guo, S Li, Y Zheng, T Li, S Zhao, D Yu, L Bai - Aquaculture, 2024 - Elsevier
To investigate the mechanism underlying immune rejection in pearl oyster Pinctada fucata
following allograft (P. fucata mantle pieces) and xenograft (P. maxima mantle pieces) …