Incompatibilities of pharmaceutical excipients with active pharmaceutical ingredients: a comprehensive review

SS Bharate, SB Bharate, AN Bajaj - Journal of Excipients and Food …, 2010 - ojs.abo.fi
Studies of drug-excipient compatibility represent an important phase in the pre-formulation
stage for the development of all dosage forms. The potential physical and chemical …

Análise térmica aplicada a fármacos e formulações farmacêuticas na indústria farmacêutica

MA Oliveira, MI Yoshida, EC Lima Gomes - Química Nova, 2011 - SciELO Brasil
Several matters of the pharmaceutical demonstrate the great importance of thermal analysis
application, especially TG and DSC for the pharmaceutical industry future, namely …

Phase transition enthalpy measurements of organic and organometallic compounds. Sublimation, vaporization and fusion enthalpies from 1880 to 2015. Part 1. C1 …

W Acree, JS Chickos - Journal of Physical and Chemical Reference …, 2016 - pubs.aip.org
A compendium of phase change enthalpies published in 2010 is updated to include the
period 1880–2015. Phase change enthalpies including fusion, vaporization, and …

Compatibility study between ketoprofen and pharmaceutical excipients used in solid dosage forms

B Tiţa, A Fuliaş, G Bandur, E Marian, D Tiţa - Journal of Pharmaceutical …, 2011 - Elsevier
Thermogravimetry/derivative thermogravimetry (TG/DTG) and differential scanning
calorimetry (DSC) techniques were used for assessing the compatibility between ketoprofen …

Application of DSC, IST, and FTIR study in the compatibility testing of nateglinide with different pharmaceutical excipients

NR Pani, LK Nath, S Acharya… - Journal of Thermal …, 2012 - akjournals.com
Experiments were done to assess the compatibility of nateglinide (NTG) with selected
excipients in the development of immediate release tablets of NTG by thermal and …

Synthesis and characterization of thiolated gum ghatti as a novel excipient: development of compression-coated mucoadhesive tablets of domperidone

V Puri, A Sharma, P Kumar, I Singh, K Huanbutta - ACS omega, 2021 - ACS Publications
Mucoadhesive polymers represent a major part of site-specific and localized retention
strategies in oral drug delivery. The present research was designed to synthesize and …

Sustained drug release behavior of captopril-incorporated chitosan/carboxymethyl cellulose biomaterials for antihypertensive therapy

KJ Kim, MJ Hwang, WG Shim, YN Youn… - International Journal of …, 2024 - Elsevier
Captopril (CTP) is an oral drug widely used to treat high blood pressure and congestive
heart failure. In this study, CTP-incorporated biomaterials for antihypertensive therapy were …

Preformulation: The use of FTIR in compatibility studies

AI Segall - 2019 - notablesdelaciencia.conicet.gov.ar
Studies of active pharmaceutical ingredient (API)-excipient compatibility represent an
important study in the preformulation stage of the development of new dosage forms. The …

Development and characterization of orally disintegrating tablets containing a captopril-cyclodextrin complex

AM Musuc, V Anuta, I Atkinson, VT Popa, I Sarbu… - Pharmaceutics, 2020 - mdpi.com
Captopril is the first angiotensin I-converting enzyme inhibitor widely used for the treatment
of hypertension. Based on the well-known benefits of cyclodextrin inclusion complexes, the …

Development of chondroitin sulfate-based mucoadhesive interpenetrating polymeric hydrogels of captopril with adjustable properties as gastro-retentive sustained …

R Qaiser, F Pervaiz, H Hanan, H Shoukat, M Nadeem - Polymer Bulletin, 2024 - Springer
In this research, we demonstrated a chondroitin sulfate (CHS), polyvinylpyrrolidone (PVP),
and 2-acrylamide-2-methylpropane sulphonic acid (AMPS)-based captopril-loaded …