Contrast-induced nephropathy: Basic concepts, pathophysiological implications and prevention strategies

C Mamoulakis, K Tsarouhas, I Fragkiadoulaki… - Pharmacology & …, 2017 - Elsevier
Contrast-induced nephropathy (CIN) is reversible acute renal failure observed following
administration of iodinated contrast media (CM) during angiographic or other medical …

Prevention of contrast‐induced nephropathy through a knowledge of its pathogenesis and risk factors

M Andreucci, T Faga, A Pisani… - The Scientific World …, 2014 - Wiley Online Library
Contrast‐induced nephropathy (CIN) is an iatrogenic acute renal failure (ARF) occurring
after the intravascular injection of iodinated radiographic contrast media. During the past …

Bridging translation by improving preclinical study design in AKI

M De Caestecker, BD Humphreys, KD Liu… - Journal of the …, 2015 - journals.lww.com
Despite extensive research, no therapeutic interventions have been shown to prevent AKI,
accelerate recovery of AKI, or reduce progression of AKI to CKD in patients. This failure in …

Update on the renal toxicity of iodinated contrast drugs used in clinical medicine

M Andreucci, T Faga, R Serra, G De Sarro… - Drug, healthcare and …, 2017 - Taylor & Francis
An important side effect of diagnostic contrast drugs is contrast-induced acute kidney injury
(CI-AKI; a sudden decrease in renal function) occurring 48–72 hours after injection of a …

Histopathological evaluation of contrast‐induced acute kidney injury rodent models

N Kiss, P Hamar - BioMed research international, 2016 - Wiley Online Library
Contrast‐induced acute kidney injury (CI‐AKI) can occur in 3–25% of patients receiving
radiocontrast material (RCM) despite appropriate preventive measures. Often patients with …

[HTML][HTML] The efficacy of sodium bicarbonate in preventing contrast-induced nephropathy in patients with pre-existing renal insufficiency: a meta-analysis

B Zhang, L Liang, W Chen, C Liang, S Zhang - BMJ open, 2015 - bmjopen.bmj.com
Objective The aim of this meta-analysis was to explore the efficacy of sodium bicarbonate in
preventing contrast-induced nephropathy (CIN). Methods We searched PubMed, Medline …

Comparison of normal saline, ringer's lactate, and sodium bicarbonate for prevention of contrast-induced nephropathy in patients with coronary angiography: a …

M Pakfetrat, L Malekmakan, Z Salmanpour… - Indian Journal of …, 2019 - journals.lww.com
Contrast-induced nephropathy (CIN) is one the most important renal complications following
contrast injection in percutaneous coronary intervention. We compared the protective effect …

Impact on clinical practice of updated guidelines on iodinated contrast material: CINART

EC Nijssen, PJ Nelemans, RJ Rennenberg… - European …, 2020 - Springer
Objective Guidelines on safe use of iodinated contrast material recommend intravenous
prophylactic hydration to prevent post-contrast adverse (renal) effects. Recently, guidelines …

Post-contrast acute kidney injury and intravenous prophylactic hydration: an update

EC Nijssen, R Rennenberg, P Nelemans… - RöFo-Fortschritte auf …, 2021 - thieme-connect.com
Background Despite tremendous improvement in molecular properties over the last century,
intravascular injection of iodinated contrast material may still have systemic and …

Incomplete Recovery from the Radiocontrast-Induced Dysregulated Cell Cycle, Adhesion, and Fibrogenesis in Renal Tubular Cells after Radiocontrast (Iohexol) …

HY Chen, YH Wu, CY Wei, ZY Liao, HT Wu… - International Journal of …, 2023 - mdpi.com
Contrast-induced nephropathy (CIN) is one of the most common causes of acute kidney
injury (AKI). However, management is still limited, and the cellular response to radiocontrast …