Metabolites produced by the host and microbiota play a crucial role in how human bodies
develop and remain healthy. Most of these metabolites are produced by microbiota and …

The rapid evolution of antibiotic resistance and the complicated bacterial infection
microenvironments are serious obstacles to traditional antibiotic therapy. Developing novel …

Metabolic adaptations regulate the response of macrophages to infection. The contributions
of metabolism to macrophage interactions with the emerging fungal pathogen Candida auris …

Tuberculosis (TB), which is caused by Mycobacterium tuberculosis (Mtb), is one of the most
lethal infectious disease worldwide, and it greatly affects human health. Some diagnostic …

Background Treatment of brain tumors, epilepsy, or hemodynamic abnormalities requires a
craniotomy to access the brain. Nearly 1 million craniotomies are performed in the US …

Achieving efficient hemostasis and wound management is vital to preserve life and restore
health in case of extensive hemorrhagic skin damage. Here, we develop a filter pump-like …

Sepsis is a leading cause of in‐hospital mortality resulting from a dysregulated response to
infection. Novel immunomodulatory therapies targeting macrophage metabolism have …

Cells living in geometrically confined microenvironments are ubiquitous in various
physiological processes, eg, wound closure. However, it remains unclear whether and how …

Abstract Implant‐related infections (IRIs), characterized by the formation of bacterial biofilms
and immunosuppressive microenvironment, are a common but tricky clinical issue. In this …

H-NS, the histone-like nucleoid-structuring protein in bacteria, regulates the stability of the
bacterial genome by inhibiting the transcription of horizontally transferred genes, such as the …