The delivery of drugs to tumors by nanoparticles is a rapidly growing field. However, the
complex tumor microenvironment (TME) barriers greatly hinder drug delivery to tumors. In …

Recent developments in nanotechnology have brought new approaches to cancer
diagnosis and therapy. While enhanced permeability and retention effect promotes nano …

Recent days, aggregatable nanoparticles, which can specifically respond to certain stimulus,
have shown great potential in tumor-targeted drug delivery with prolonged retention and …

The limited penetration of nanoparticles in primary tumors and metastases remains a great
challenge for effective treatment of tumor metastasis. This review outlines the current …

Insufficient drug accumulation and chemoresistance remain two major challenges in cancer
chemotherapy. Herein, we designed a furin-responsive aggregated nanoplatform loaded …

Remarkable advances in nano delivery systems have provided new hope for tumor
prevention, diagnosis and treatment. However, only limited clinical therapeutic effects …

Breast cancer is the most common tumor in women, and the metastasis further increases the
malignancy with extremely high mortality. However, there is almost no effective method in …

Collagen and hyaluronan are the most abundant components of the extracellular matrix
(ECM) and their overexpression in tumors is linked to increased tumor growth and …

Over the past three decades, nanoscience has offered a unique solution for reducing the
systemic toxicity of chemotherapy drugs and for increasing drug therapeutic efficiency …

Over recent years, advancements in nanomedicine have allowed new approaches to
diagnose and treat tumors. Nano drug delivery systems exploit the enhanced permeability …