[HTML][HTML] What is a cell type and how to define it?
H Zeng - Cell, 2022 - cell.com
Cell types are the basic functional units of an organism. Cell types exhibit diverse
phenotypic properties at multiple levels, making them challenging to define, categorize, and …
phenotypic properties at multiple levels, making them challenging to define, categorize, and …
Insights into Alzheimer's disease from single-cell genomic approaches
MH Murdock, LH Tsai - Nature neuroscience, 2023 - nature.com
Alzheimer's disease (AD) is an age-related disease pathologically defined by the deposition
of amyloid plaques and neurofibrillary tangles in the brain parenchyma. Single-cell profiling …
of amyloid plaques and neurofibrillary tangles in the brain parenchyma. Single-cell profiling …
Molecularly defined and spatially resolved cell atlas of the whole mouse brain
In mammalian brains, millions to billions of cells form complex interaction networks to enable
a wide range of functions. The enormous diversity and intricate organization of cells have …
a wide range of functions. The enormous diversity and intricate organization of cells have …
The emergence and influence of internal states
Animal behavior is shaped by a variety of" internal states"—partially hidden variables that
profoundly shape perception, cognition, and action. The neural basis of internal states, such …
profoundly shape perception, cognition, and action. The neural basis of internal states, such …
Molecularly targetable cell types in mouse visual cortex have distinguishable prediction error responses
Predictive processing postulates the existence of prediction error neurons in cortex. Neurons
with both negative and positive prediction error response properties have been identified in …
with both negative and positive prediction error response properties have been identified in …
Spatial omics technologies at multimodal and single cell/subcellular level
Spatial omics technologies enable a deeper understanding of cellular organizations and
interactions within a tissue of interest. These assays can identify specific compartments or …
interactions within a tissue of interest. These assays can identify specific compartments or …
Cortical somatostatin interneuron subtypes form cell-type-specific circuits
The cardinal classes are a useful simplification of cortical interneuron diversity, but such
broad subgroupings gloss over the molecular, morphological, and circuit specificity of …
broad subgroupings gloss over the molecular, morphological, and circuit specificity of …
Spatial transcriptomics: technical aspects of recent developments and their applications in neuroscience and cancer research
Spatial transcriptomics is a newly emerging field that enables high‐throughput investigation
of the spatial localization of transcripts and related analyses in various applications for …
of the spatial localization of transcripts and related analyses in various applications for …
Multimodal mapping of cell types and projections in the central nucleus of the amygdala
The central nucleus of the amygdala (CEA) is a brain region that integrates external and
internal sensory information and executes innate and adaptive behaviors through distinct …
internal sensory information and executes innate and adaptive behaviors through distinct …
Mapping visual functions onto molecular cell types in the mouse superior colliculus
The superficial superior colliculus (sSC) carries out diverse roles in visual processing and
behaviors, but how these functions are delegated among collicular neurons remains …
behaviors, but how these functions are delegated among collicular neurons remains …