Aging is an inevitable outcome of life, characterized by a progressive decline in tissue and
organ function. At a molecular level, it is marked by the gradual alterations of biomolecules …

Paget's disease of bone (PDB) is the second most prevalent metabolic bone disorder
worldwide, with a prevalence rate of 1.5%–8.3%. It is characterized by localized areas of …

Women experience osteoporosis at higher rates than men. Aside from hormones, the
mechanisms driving sex-dependent bone mass regulation are not well understood. Here …

Bone remodeling is a continuous and dynamic process of bone formation and resorption to
maintain its integrity and homeostasis. Bone marrow is a source of various cell lineages …

Bone metabolism consists of a balance between bone formation and bone resorption, which
is mediated by osteoblast and osteoclast activity, respectively. In order to ensure bone …

Context Measurement of circulating microRNAs (miRNAs) as potential biomarkers of fragility
fracture risk has recently become a subject of investigation. Objective Measure by next …

Background Dysfunction in the osteogenic differentiation of bone marrow mesenchymal
stem cells (BMSCs) leads to bone loss/osteoporosis. The catenin beta interacting protein 1 …

Osteoporosis is a widespread systemic disease characterized by a decrease in bone mass
and an imbalance of the microarchitecture of bone tissue. Experimental and clinical studies …

The L enantiomer of β aminoisobutyric acid (BAIBA) is secreted by contracted muscle in
mice, and exercise increases serum levels in humans. In mice, L BAIBA reduces bone loss …

Objectives. Thyroid hormone is acknowledged as a pivotal factor in skeletal development
and adult bone maintenance. However, available data about the relationship between …