[HTML][HTML] Calcineurin: the Achilles' heel of fungal pathogens

V Yadav, J Heitman - PLoS Pathogens, 2023 - journals.plos.org
Calcineurin is a highly conserved serine-threonine specific protein phosphatase and was
named based on its discovery as a calcium-and calmodulin-binding protein that is highly …

Casein kinase 2 complex: a central regulator of multiple pathobiological signaling pathways in Cryptococcus neoformans

Y Choi, SR Yu, Y Lee, AY Na, S Lee, J Heitman, R Seo… - Mbio, 2024 - Am Soc Microbiol
ABSTRACT The casein kinase 2 (CK2) complex has garnered extensive attention over the
past decades as a potential therapeutic target for diverse human diseases, including cancer …

[HTML][HTML] Transcriptional and Post-Translational Roles of Calcineurin in Cationic Stress and Glycerol Biosynthesis in Cryptococcus neoformans

RS Santos, G Martins-Silva, AAÁ Padilla, M Possari… - Journal of Fungi, 2024 - mdpi.com
Stress management is an adaptive advantage for survival in adverse environments.
Pathogens face this challenge during host colonization, requiring an appropriate stress …