Strategies for functionalizing diverse tetrahedral framework nucleic acids (tFNAs) have been
extensively explored since the first successful fabrication of tFNA by Turberfield. Onepot …

DNA, a genetic material, has been employed in different scientific directions for various
biological applications as driven by DNA nanotechnology in the past decades, including …

DNA nanotechnology has progressed from proof-of-concept demonstrations of structural
design towards application-oriented research. As a natural material with excellent self …

Tetrahedral DNA nanostructures (TDNs) are considered promising drug delivery carriers
because they are able to permeate cellular membrane and are biocompatible and …

With the emergence of DNA nanotechnology in the 1980s, self-assembled DNA
nanostructures have attracted considerable attention worldwide due to their inherent …

One of the biggest obstacles for the use of antisense oligonucleotides as antibacterial
therapeutics is their limited uptake by bacterial cells without a suitable carrier, especially in …

Paclitaxel (PTX) is an effective drug against diseases such as lung cancer, ovarian cancer,
and breast cancer. However, multidrug resistance limits the clinical applications of this drug …

Tetrahedral DNA nanostructures (TDNs) are a new type of nanomaterials that have recently
attracted attention in the field of biomedicine. However, the practical application of …

Osteoarthritis, a disorder characterized by articular cartilage deterioration, varying degrees
of inflammation, and chondrocyte apoptosis, is the most common chronic joint disease. To …

The effective regeneration of weightbearing bone defects and criticalsized cartilage
defects remains a significant clinical challenge. Traditional treatments such as autologous …