Macrophage polarization states in the tumor microenvironment

AJ Boutilier, SF Elsawa - International journal of molecular sciences, 2021 - mdpi.com
The M1/M2 macrophage paradigm plays a key role in tumor progression. M1 macrophages
are historically regarded as anti-tumor, while M2-polarized macrophages, commonly …

Redefining tumor-associated macrophage subpopulations and functions in the tumor microenvironment

K Wu, K Lin, X Li, X Yuan, P Xu, P Ni, D Xu - Frontiers in immunology, 2020 - frontiersin.org
The immunosuppressive status of the tumor microenvironment (TME) remains poorly
defined due to a lack of understanding regarding the function of tumor-associated …

The role of the immune microenvironment in bone, cartilage, and soft tissue regeneration: from mechanism to therapeutic opportunity

Y Xiong, BB Mi, Z Lin, YQ Hu, L Yu, KK Zha… - Military Medical …, 2022 - Springer
Bone, cartilage, and soft tissue regeneration is a complex spatiotemporal process recruiting
a variety of cell types, whose activity and interplay must be precisely mediated for effective …

Macrophage plasticity, polarization, and function in health and disease

A Shapouri‐Moghaddam… - Journal of cellular …, 2018 - Wiley Online Library
Macrophages are heterogeneous and their phenotype and functions are regulated by the
surrounding micro‐environment. Macrophages commonly exist in two distinct subsets: 1) …

[HTML][HTML] Berry polyphenols and human health: Evidence of antioxidant, anti-inflammatory, microbiota modulation, and cell-protecting effects

N Pap, M Fidelis, L Azevedo, MAV do Carmo… - Current Opinion in Food …, 2021 - Elsevier
Highlights•Berries have in vitro and in vivo antioxidant properties.•Studies reveal in vitro and
in vivo anti-hypertensive and antihyperglycemic activities.•Berries modulate pro …

[HTML][HTML] Inflammatory responses and inflammation-associated diseases in organs

L Chen, H Deng, H Cui, J Fang, Z Zuo, J Deng, Y Li… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Inflammation is a biological response of the immune system that can be triggered by a
variety of factors, including pathogens, damaged cells and toxic compounds. These factors …

A critical review on the health benefits of fish consumption and its bioactive constituents

J Chen, M Jayachandran, W Bai, B Xu - Food Chemistry, 2022 - Elsevier
As one of food sources, fish provides sufficient nutrition to human. Diverse nutrients in fish
make fish an important nutrient source available easily across the globe. Fish is proven to …

[HTML][HTML] Fibronectin in development and wound healing

J Patten, K Wang - Advanced drug delivery reviews, 2021 - Elsevier
Fibronectin structure and composition regulate contextual cell signaling. Recent advances
have been made in understanding fibronectin and its role in tissue organization and repair …

[HTML][HTML] Low dose ionizing radiation effects on the immune system

K Lumniczky, N Impens, G Armengol, S Candéias… - Environment …, 2021 - Elsevier
Ionizing radiation interacts with the immune system in many ways with a multiplicity that
mirrors the complexity of the immune system itself: namely the need to maintain a delicate …

Hyperglycemia and oxidative stress: An integral, updated and critical overview of their metabolic interconnections

P González, P Lozano, G Ros, F Solano - International Journal of …, 2023 - mdpi.com
This review focuses on the multiple and reciprocal relationships that exist between oxidative
stress, hyperglycemia and diabetes and related metabolic disorders. Human metabolism …