Comparison of gefitinib, erlotinib and afatinib in non‐small cell lung cancer: a meta‐analysis

Z Yang, A Hackshaw, Q Feng, X Fu… - … journal of cancer, 2017 - Wiley Online Library
Gefitinib, erlotinib and afatinib are three widely used epidermal growth factor receptor
tyrosine kinase inhibitors (EGFR TKIs) for treating advanced non‐small cell lung cancer …

[HTML][HTML] Molecular targeted drugs and biomarkers in NSCLC, the evolving role of individualized therapy

K Domvri, P Zarogoulidis, K Darwiche… - Journal of …, 2013 - ncbi.nlm.nih.gov
Lung cancer first line treatment has been directed from the non-specific cytotoxic doublet
chemotherapy to the molecular targeted. The major limitation of the targeted therapies still …

Gefitinib and erlotinib in metastatic non-small cell lung cancer: a meta-analysis of toxicity and efficacy of randomized clinical trials

M Burotto, EE Manasanch, J Wilkerson, T Fojo - The oncologist, 2015 - academic.oup.com
Abstract Background. Tyrosine kinase inhibitors (TKIs) targeting the epidermal growth factor
receptor (EGFR) have been evaluated in patients with metastatic and advanced non-small …

[HTML][HTML] Update of epidermal growth factor receptor-tyrosine kinase inhibitors in non-small-cell lung cancer

YM Chen - Journal of the Chinese medical Association, 2013 - Elsevier
Lung cancer is the leading cause of cancer-related death in the world. Prior to the era of
targeted therapy, platinum-based doublet chemotherapy was the first-line therapy of choice …

Comparison of effectiveness and adverse effects of gefitinib, erlotinib and icotinib among patients with non‑small cell lung cancer: A network meta‑analysis

Y Liu, Y Zhang, G Feng, Q Niu… - Experimental and …, 2017 - spandidos-publications.com
The present network meta‑analysis aimed to compare the effectiveness and adverse effects
of gefitinib, erlotinib and icotinib in the treatment of patients with non‑small cell lung cancer …

Gefitinib provides similar effectiveness and improved safety than erlotinib for east Asian populations with advanced non–small cell lung cancer: a meta-analysis

W Zhang, Y Wei, D Yu, J Xu, J Peng - BMC cancer, 2018 - Springer
Background The first-generation epidermal growth factor receptor tyrosine kinase inhibitors
gefitinib and erlotinib have both been proven effective for treating advanced non–small cell …

[HTML][HTML] Development and application of an HPLC method for erlotinib protein binding studies

S Bolandnazar, A Divsalar, H Valizadeh… - Advanced …, 2013 - ncbi.nlm.nih.gov
Purpose: The aim of the present study was to develop a simple and rapid reversed-phase
high performance liquid chromatographic method with UV detection for erlotinib …

Gefitinib provides similar effectiveness and improved safety than erlotinib for advanced non-small cell lung cancer: A meta-analysis

W Zhang, Y Wei, D Yu, J Xu, J Peng - Medicine, 2018 - journals.lww.com
Background: The epidermal growth factor receptor tyrosine kinase inhibitors gefitinib and
erlotinib are effective for advanced non-small cell lung cancer (NSCLC). This meta-analysis …

晚期非小细胞肺癌基本证型探讨

龚亚斌, 王中奇, 赵晓珍, 邓海滨, 苏婉, 王立芳… - 上海中医药大学 …, 2012 - cqvip.com
目的: 探讨晚期非小细胞肺癌(non-small cell lung cancer, NSCLC) 的基本中医证型. 方法:
纳入晚期NSCLC 患者338 例, 收集患者的临床症状, 应用因子分析方法对症状进行分类 …

Erlotinib has better efficacy than gefitinib in adenocarcinoma patients without EGFR-activating mutations, but similar efficacy in patients with EGFR-activating …

WS Wu, YM Chen, CM Tsai… - Experimental and …, 2012 - spandidos-publications.com
Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) are an effective
treatment for advanced non-small cell lung cancer. The objective of the present study was to …