Biomarkers and Algorithms for the Diagnosis of Vitamin B12 Deficiency
L Hannibal, V Lysne, AL Bjørke-Monsen… - Frontiers in molecular …, 2016 - frontiersin.org
Vitamin B12 (cobalamin, Cbl, B12) is an indispensable water-soluble micronutrient that
serves as a coenzyme for cytosolic methionine synthase (MS) and mitochondrial …
serves as a coenzyme for cytosolic methionine synthase (MS) and mitochondrial …
Vitamin B12 deficiency
Abstract Vitamin B 12 (B12; also known as cobalamin) is a B vitamin that has an important
role in cellular metabolism, especially in DNA synthesis, methylation and mitochondrial …
role in cellular metabolism, especially in DNA synthesis, methylation and mitochondrial …
“Classical organic acidurias”: diagnosis and pathogenesis
Organic acidurias are inherited metabolic diseases due to the deficiency of an enzyme or a
transport protein involved in one of the several cellular metabolic pathways devoted to the …
transport protein involved in one of the several cellular metabolic pathways devoted to the …
The inorganic chemistry of the cobalt corrinoids–an update
HM Marques - Journal of Inorganic Biochemistry, 2023 - Elsevier
The inorganic chemistry of the cobalt corrinoids, derivatives of vitamin B 12, is reviewed, with
particular emphasis on equilibrium constants for, and kinetics of, their axial ligand …
particular emphasis on equilibrium constants for, and kinetics of, their axial ligand …
Analysis of S-adenosylmethionine and S-adenosylhomocysteine: method optimisation and profiling in healthy adults upon short-term dietary intervention
AC Bravo, MNL Aguilera, NR Marziali, L Moritz… - Metabolites, 2022 - mdpi.com
S-adenosylmethionine (SAM) is essential for methyl transfer reactions. All SAM is produced
de novo via the methionine cycle. The demethylation of SAM produces S …
de novo via the methionine cycle. The demethylation of SAM produces S …
Antivitamins B12—A Structure‐ and Reactivity‐Based Concept
B Kräutler - Chemistry–A European Journal, 2015 - Wiley Online Library
B12‐antimetabolites are compounds that counteract the physiological effects of vitamin B12
and related natural cobalamins. Presented here is a structure‐and reactivity‐based concept …
and related natural cobalamins. Presented here is a structure‐and reactivity‐based concept …
Cobalamin Protection against Oxidative Stress in the Acidophilic Iron-oxidizing Bacterium Leptospirillum Group II CF-1
A Ferrer, J Rivera, C Zapata, J Norambuena… - Frontiers in …, 2016 - frontiersin.org
Members of the genus Leptospirillum are aerobic iron-oxidizing bacteria belonging to the
phylum Nitrospira. They are important members of microbial communities that catalyze the …
phylum Nitrospira. They are important members of microbial communities that catalyze the …
Nitric oxide homeostasis in neurodegenerative diseases
L Hannibal - Current Alzheimer Research, 2016 - ingentaconnect.com
The role of nitric oxide in the pathogenesis and progression of neurodegenerative illnesses
such as Parkinson's and Alzheimer's diseases has become prominent over the years …
such as Parkinson's and Alzheimer's diseases has become prominent over the years …
Inherited disorders of cobalamin metabolism disrupt nucleocytoplasmic transport of mRNA through impaired methylation/phosphorylation of ELAVL1/HuR
SF Battaglia-Hsu, R Ghemrawi, D Coelho… - Nucleic acids …, 2018 - academic.oup.com
The molecular mechanisms that underlie the neurological manifestations of patients with
inherited diseases of vitamin B12 (cobalamin) metabolism remain to date obscure. We …
inherited diseases of vitamin B12 (cobalamin) metabolism remain to date obscure. We …
Altered Redox Homeostasis in Branched‐Chain Amino Acid Disorders, Organic Acidurias, and Homocystinuria
E Richard, L Gallego-Villar… - Oxidative Medicine …, 2018 - Wiley Online Library
Inborn errors of metabolism (IEMs) are a group of monogenic disorders characterized by
dysregulation of the metabolic networks that underlie development and homeostasis …
dysregulation of the metabolic networks that underlie development and homeostasis …