DNA methyltransferases: from evolution to clinical applications

VM Del Castillo Falconi, K Torres-Arciga… - International journal of …, 2022 - mdpi.com
DNA methylation is an epigenetic mark that living beings have used in different
environments. The MTases family catalyzes DNA methylation. This process is conserved …

Small RNAs and chromatin in the multigenerational epigenetic landscape of Caenorhabditis elegans

N Frolows, A Ashe - … Transactions of the Royal Society B, 2021 - royalsocietypublishing.org
For decades, it was thought that the only heritable information transmitted from one
individual to another was that encoded in the DNA sequence. However, it has become …

The admixed brushtail possum genome reveals invasion history in New Zealand and novel imprinted genes

DM Bond, O Ortega-Recalde, MK Laird… - Nature …, 2023 - nature.com
Combining genome assembly with population and functional genomics can provide
valuable insights to development and evolution, as well as tools for species management …

Mechanisms of transgenerational epigenetic inheritance: lessons from animal model organisms

F Santilli, A Boskovic - Current Opinion in Genetics & Development, 2023 - Elsevier
Epigenetic inheritance is a phenomenon whereby stochastic or signal-induced changes to
parental germline epigenome modulate phenotypic output in one or more subsequent …

[HTML][HTML] Cell-type-specific responses to the microbiota across all tissues of the larval zebrafish

MS Massaquoi, GL Kong, D Chilin-Fuentes, JS Ngo… - Cell reports, 2023 - cell.com
Animal development proceeds in the presence of intimate microbial associations, but the
extent to which different host cells across the body respond to resident microbes remains to …

Parental mutations influence wild-type offspring via transcriptional adaptation

Z Jiang, MA El-Brolosy, V Serobyan, JM Welker… - Science …, 2022 - science.org
Transgenerational epigenetic inheritance (TEI) is mostly discussed in the context of
physiological or environmental factors. Here, we show intergenerational and …

[HTML][HTML] Paternal transgenerational nutritional epigenetic effect: A new insight into nutritional manipulation to reduce the use of antibiotics in animal feeding

X Li, M Wang, S Liu, X Chen, Y Qiao, X Yang, J Yao… - Animal Nutrition, 2022 - Elsevier
The use of antibiotics in animal feeding has been banned in many countries because of
increasing concerns about the development of bacterial resistance to antibiotics and …

Global expression pattern of genes containing positively selected sites in European anchovy (Engraulis encrasicolus L.) may shed light on teleost reproduction

V Eldem, G Zararsız, M Erkan - PloS one, 2023 - journals.plos.org
European anchovy is a multiple-spawning and highly fecundate pelagic fish with high
economic and ecological significance. Although fecundity is influenced by nutrition …

[HTML][HTML] Aging of common carp (Cyprinus carpio L.) sperm induced by short-term storage does not alter global DNA methylation and specific histone modifications in …

Y Cheng, SG Waghmare, S Zhang, P Vechtová… - Aquaculture, 2023 - Elsevier
Short-term storage of sperm is a useful tool to synchronize the availability of male and
female gametes for fertilization in a hatchery. Induced aging by short-term storage has been …

Genetic landscape of T cells identifies synthetic lethality for T-ALL

CP O'Meara, L Guerri, DF Lawir, F Mateos… - Communications …, 2021 - nature.com
To capture the global gene network regulating the differentiation of immature T cells in an
unbiased manner, large-scale forward genetic screens in zebrafish were conducted and …