[HTML][HTML] Rethinking the initial changes in subarachnoid haemorrhage: focusing on real-time metabolism during early brain injury

Y Chen, I Galea, RL Macdonald, GKC Wong… - …, 2022 - thelancet.com
Over the last two decades, neurological researchers have uncovered many
pathophysiological mechanisms associated with subarachnoid haemorrhage (SAH), with …

[HTML][HTML] Systemic inflammation after aneurysmal subarachnoid hemorrhage

CZ Chai, UC Ho, LT Kuo - International Journal of Molecular Sciences, 2023 - mdpi.com
Aneurysmal subarachnoid hemorrhage (aSAH) is one of the most severe neurological
disorders, with a high mortality rate and severe disabling functional sequelae. Systemic …

Subarachnoid blood clearance and aneurysmal subarachnoid hemorrhage outcomes: a retrospective review

HA Zeineddine, A Divito, DW McBride, P Pandit… - Neurocritical Care, 2023 - Springer
Background Delayed cerebral ischemia (DCI) continues to be a significant contributor to
morbidity and mortality following aneurysmal subarachnoid hemorrhage (aSAH) …

[HTML][HTML] Diagnosis potential of subarachnoid hemorrhage using miRNA signatures isolated from plasma-derived extracellular vesicles

B Sheng, N Lai, T Tao, X Chen, S Gao, Q Zhu… - Frontiers in …, 2023 - frontiersin.org
The diagnosis and clinical management of aneurysmal subarachnoid hemorrhage (aSAH) is
currently limited by the lack of accessible molecular biomarkers that reflect the …

Mitochondrial dysfunction and quality control lie at the heart of subarachnoid hemorrhage

J Zhang, Q Zhu, J Wang, Z Peng… - Neural Regeneration …, 2023 - journals.lww.com
The dramatic increase in intracranial pressure after subarachnoid hemorrhage leads to a
decrease in cerebral perfusion pressure and a reduction in cerebral blood flow …

Neutrophils and neutrophil extracellular traps cause vascular occlusion and delayed cerebral ischemia after subarachnoid hemorrhage in mice

HA Zeineddine, SH Hong, P Peesh… - … and Vascular Biology, 2024 - Am Heart Assoc
BACKGROUND: After subarachnoid hemorrhage (SAH), neutrophils are deleterious and
contribute to poor outcomes. Neutrophils can produce neutrophil extracellular traps (NETs) …

Association of hemoglobin drift and outcomes in patients with aneurysmal subarachnoid hemorrhage

X Wang, Q Gan, X Qiu, W Chen, D Wen, C You… - Neurosurgical …, 2024 - Springer
The relationship between in-hospital hemoglobin (Hb) drift and outcomes in patients
undergoing surgical clipping for aneurysmal subarachnoid hemorrhage (aSAH) is not well …

Microclots in subarachnoid hemorrhage: an underestimated factor in delayed cerebral ischemia?

M Monsour, DM Croci, S Agazzi - Clinical Neurology and Neurosurgery, 2022 - Elsevier
Subarachnoid hemorrhage has a poor prognosis due to the wide array of associated
complications such as vasospasm, early brain injury, cortical spreading depression …

How to promote hemoglobin scavenging or clearance and detoxification in hemorrhagic stroke

H Suzuki - Translational Stroke Research, 2023 - Springer
Hemorrhagic strokes such as intracerebral hemorrhage (ICH) and subarachnoid
hemorrhage (SAH) are common diseases, but their effective treatments are limited. As a …

[HTML][HTML] Metabolomics as a potential tool for monitoring patients with aneurysmal subarachnoid hemorrhage

N Lasica, V Raicevic, NM Stojanovic, D Djilvesi… - Frontiers in …, 2023 - frontiersin.org
Metabolomics has evolved into a particularly useful tool to study interactions between
metabolites and serves as an aid in unraveling the complexity of entire metabolomes …