Many widely used medications may cause or exacerbate a variety of arrhythmias. Numerous
antiarrhythmic agents, antimicrobial drugs, psychotropic medications, and methadone, as …

Atherosclerosis represents a significant cause of morbidity and mortality in both the
developed and developing countries. Animal models of atherosclerosis have served as …

Background The T peak− T end interval (the interval from the peak to the end of the T wave),
an electrocardiographic marker reflecting transmural dispersion of repolarization, has been …

The emergence of human induced pluripotent stem cells (hiPSCs) and efficient
differentiation of hiPSC-derived cardiomyocytes (hiPSC-CMs) induced from diseased …

Brugada syndrome (BrS) is an inherited ion channel channelopathy predisposing to
ventricular arrhythmias and sudden cardiac death. Originally believed to be predominantly …

Brugada syndrome (BrS) is a fatal arrhythmia that causes an estimated 4% of all sudden
death in high-incidence areas. SCN5A encodes cardiac sodium channel NaV1. 5 and …

In this work, we reported a computational study to quantitatively determine the individual
contributions of three candidate arrhythmic factors associated with Brugada Syndrome. In …

Prompt diagnosis of acute ST segment elevation myocardial infarction (STEMI) by the initial
ECG is important in order to perform an urgent coronary angiography as soon as possible …

Background A combination of clinical and electrocardiographic risk factors is used for risk
stratification in Brugada syndrome. In this study, we tested the hypothesis that the …

There is a need for improved in vitro models of inherited cardiac diseases to better
understand basic cellular and molecular mechanisms and advance drug development. Most …