Esophageal cancer: emerging therapeutics

JE Rogers, M Sewastjanow-Silva… - Expert opinion on …, 2022 - Taylor & Francis
Introduction Esophageal cancer (EC) is a worldwide healthcare concern and represents an
aggressive malignancy. Squamous cell carcinoma (ESCC) and adenocarcinoma (EAC) are …

cGAS–STING signaling pathway in gastrointestinal inflammatory disease and cancers

X Ke, T Hu, M Jiang - The FASEB Journal, 2022 - Wiley Online Library
Abstract Cyclic GMP‐AMP synthase (cGAS)–stimulator of interferon genes (STING)
signaling pathway has emerged as a key DNA‐sensing machinery in innate immunity …

Hsa_circ_0046534 accelerates esophageal squamous cell carcinoma proliferation and metastasis via regulating MMP2 expression by sponging miR-339-5p

T Xu, Y Hu, Y Zhao, Y Qi, S Zhang, P Li - Cellular Signalling, 2023 - Elsevier
Esophageal cancer is one of the most malignant gastrointestinal malignancies. Esophageal
squamous cell carcinoma (ESCC) is the most common type of esophageal cancer in China …

[Retracted] LncRNA OIP5‐AS1 Knockdown Facilitated the Ferroptosis and Immune Evasion by Modulating the GPX4 in Oesophageal Carcinoma

J Hou, Q Huang, Z Fan, H Sang, S Wu… - … Methods in Medicine, 2022 - Wiley Online Library
Objective. Oesophageal cancer (EC) is an extremely invasive malignancy, which has bad
prognosis that requires safe and effective treatment modalities. Immunotherapy has …

[HTML][HTML] Establishment of prognostic risk model and drug sensitivity based on prognostic related genes of esophageal cancer

J Dai, A Reyimu, A Sun, Z Duoji, W Zhou, S Liang… - Scientific Reports, 2022 - nature.com
At present, the treatment of esophageal cancer (EC) is mainly surgical and drug treatment.
However, due to drug resistance, these therapies can not effectively improve the prognosis …

[HTML][HTML] The Role of Pentraxin 3 in Gastrointestinal Cancers

M Zajkowska, B Mroczko - Cancers, 2023 - mdpi.com
Simple Summary Gastrointestinal (GI) cancers are all malignant lesions affecting the
esophagus, stomach, liver and intrahepatic bile ducts, gallbladder, pancreas, and small and …

Circ_0001093 promotes glutamine metabolism and cancer progression of esophageal squamous cell carcinoma by targeting miR-579-3p/glutaminase axis

C Qian, Y Tong, Y Wang, X Teng, J Yao - Journal of Bioenergetics and …, 2022 - Springer
Increasing studies indicate that circular RNAs (circRNAs) play critical roles in tumor
metabolism of multiple cancers. However, the contribution of circRNAs in glutamine …

Harnessing the supremacy of MEG3 LncRNA to defeat gastrointestinal malignancies

HH Rashwan, AM Taher, HA Hassan, AA Awaji… - … -Research and Practice, 2024 - Elsevier
Evidence suggests that long non-coding RNAs (lncRNAs) play a pivotal role in the
carcinogenesis and progression of various human malignancies including gastrointestinal …

[HTML][HTML] DEPDC1B collaborates with GABRD to regulate ESCC progression

Y Yuan, W Ping, R Zhang, Z Hao, N Zhang - Cancer Cell International, 2022 - Springer
Esophageal squamous cell carcinoma (ESCC) is the leading cause of cancer-related death
worldwide with a poor prognosis. Given that DEPDC1B plays a key role in multiple cancers …

[HTML][HTML] Trends in esophageal adenocarcinoma and esophageal squamous cell carcinoma incidence in the United States from 1992 to 2019

KS Liu, SA Raza, HB El-Serag, AP Thrift - Cancers, 2022 - mdpi.com
Simple Summary The incidence of esophageal cancer overall has increased in the United
States, driven by increasing rates of esophageal adenocarcinoma (EAC). However, whether …