The outstanding acuity of the mammalian ear relies on cochlear amplification, an active
mechanism based on the electromotility (eM) of outer hair cells. eM is a piezoelectric …

Members of the SLC26 family constitute a conserved class of anion transport proteins, which
encompasses uncoupled transporters with channel-like properties, coupled exchangers and …

Solute carrier family 26 member 4 (SLC26A4) is a member of the SLC26A transporter family
and is expressed in various tissues, including the airway epithelium, kidney, thyroid, and …

Prestin (SLC26A5)-mediated voltage-driven elongations and contractions of sensory outer
hair cells within the organ of Corti are essential for mammalian cochlear amplification …

Abstract Solute carrier family 26 (SLC26) is a family of functionally diverse anion
transporters found in all kingdoms of life. Anions transported by SLC26 proteins include …

Abstract Pendrin (SLC26A4) is an anion exchanger that mediates bicarbonate (HCO3−)
exchange for chloride (Cl−) and is crucial for maintaining pH and salt homeostasis in the …

Mammalian SLC26 proteins are membrane-based anion transporters that belong to the
large SLC26/SulP family, and many of their variants are associated with hereditary diseases …

Pendrin and prestin are evolutionary-conserved membrane proteins that are essential for
normal hearing. Dysfunction of these proteins results in hearing loss in humans, and …

From the time of conception until the time of labor, a woman's body and mind undergo a
variety of hormonal and other changes. Patients may also experience vertigo and a lack of …