[HTML][HTML] Endocannabinoid system as a promising therapeutic target in inflammatory bowel disease–a systematic review
S Hryhorowicz, M Kaczmarek-Ryś, A Zielińska… - Frontiers in …, 2021 - frontiersin.org
Inflammatory bowel disease (IBD) is a general term used to describe a group of chronic
inflammatory conditions of the gastrointestinal tract of unknown etiology, including two …
inflammatory conditions of the gastrointestinal tract of unknown etiology, including two …
[HTML][HTML] Perineural invasion in pancreatic ductal adenocarcinoma: from molecules towards drugs of clinical relevance
F Selvaggi, E Melchiorre, I Casari, S Cinalli, M Cinalli… - Cancers, 2022 - mdpi.com
Simple Summary A few types of cancers are currently as challenging and difficult to defeat
as pancreatic ductal adenocarcinoma. Several reasons contribute to the complexity of this …
as pancreatic ductal adenocarcinoma. Several reasons contribute to the complexity of this …
[HTML][HTML] Cannabinol: history, syntheses, and biological profile of the greatest “minor” cannabinoid
Cannabis (Cannabis sativa L.) is an outstanding source of bioactive natural products, with
more than 150 different phytocannabinoids isolated throughout the decades; however …
more than 150 different phytocannabinoids isolated throughout the decades; however …
[HTML][HTML] Cannabinoid receptor-2 attenuates neuroinflammation by promoting autophagy-mediated degradation of the NLRP3 inflammasome post spinal cord injury
F Jiang, M Xia, Y Zhang, J Chang, J Cao… - Frontiers in …, 2022 - frontiersin.org
Background Neuroinflammation following spinal cord injury (SCI) results in prolonged
neurological damage and locomotor dysfunction. Polarization of microglia is vital to …
neurological damage and locomotor dysfunction. Polarization of microglia is vital to …
[HTML][HTML] Endocannabinoid modulation in neurodegenerative diseases: In pursuit of certainty
Simple Summary Neurodegenerative diseases represent an important cause of morbidity
and mortality worldwide. Existing therapeutic options are limited and focus mostly on …
and mortality worldwide. Existing therapeutic options are limited and focus mostly on …
[HTML][HTML] Mediterranean diet and neurodegenerative diseases: the neglected role of nutrition in the modulation of the endocannabinoid system
Neurodegenerative disorders are a widespread cause of morbidity and mortality worldwide,
characterized by neuroinflammation, oxidative stress and neuronal depletion. The broad …
characterized by neuroinflammation, oxidative stress and neuronal depletion. The broad …
[HTML][HTML] Cannabidiol treatment improves metabolic profile and decreases hypothalamic inflammation caused by maternal obesity
FS Rodrigues, J Jantsch, GF Fraga, VS Dias… - Frontiers in …, 2023 - frontiersin.org
Introduction The implications of maternal overnutrition on offspring metabolic and
neuroimmune development are well-known. Increasing evidence now suggests that …
neuroimmune development are well-known. Increasing evidence now suggests that …
[HTML][HTML] Receptor-Dependent and Independent Regulation of Voltage-Gated Ca2+ Channels and Ca2+-Permeable Channels by Endocannabinoids in the Brain
T Boczek, L Zylinska - International Journal of Molecular Sciences, 2021 - mdpi.com
The activity of specific populations of neurons in different brain areas makes decisions
regarding proper synaptic transmission, the ability to make adaptations in response to …
regarding proper synaptic transmission, the ability to make adaptations in response to …
[HTML][HTML] The expanded endocannabinoid system contributes to metabolic and body mass shifts in first-episode schizophrenia: a 5-year follow-up study
M Parksepp, L Haring, K Kilk, K Koch, K Uppin… - Biomedicines, 2022 - mdpi.com
Alterations in the expanded endocannabinoid system (eECS) and cell membrane
composition have been implicated in the pathophysiology of schizophrenia spectrum …
composition have been implicated in the pathophysiology of schizophrenia spectrum …
Cannabinol Regulates the Expression of Cell Cycle-Associated Genes in Motor Neuron-like NSC-34: A Transcriptomic Analysis
A Trainito, A Gugliandolo, L Chiricosta, S Salamone… - Biomedicines, 2024 - mdpi.com
Cannabinoids are reported to have neuroprotective properties and play a role in
neurogenesis and neuroplasticity in in vitro and in vivo models. Cannabinol (CBN) is a …
neurogenesis and neuroplasticity in in vitro and in vivo models. Cannabinol (CBN) is a …