Antiphospholipid antibodies are associated with arterial and venous thrombosis, recurrent
pregnancy loss, and thrombocytopenia. Although the antibodies have not been conclusively …

Beta-2 glycoprotein I (β2GPI) is the principal target of autoantibodies in the antiphospholipid
syndrome (APS). It is abundant in human plasma and shares high homology between …

Human β 2‐glycoprotein I is a heavily glycosylated five‐domain plasma membrane‐
adhesion protein, which has been implicated in blood coagulation and clearance of …

OBJECTIVE: To investigate whether heparin and low-dose aspirin increase the pregnancy
rate in antiphospholipid antibody or antinuclear antibody–seropositive women with IVF …

Lactadherin, a glycoprotein of the milk-fat globule membrane, contains tandem C domains
with homology to discoidin-type lectins and to membrane-binding domains of blood-clotting …

We previously showed that β2-glycoprotein I (β2GPI)–dependent lupus anticoagulants (LAs)
form bivalent antigen-antibody complexes with high affinity for phospholipids; these …

Objective: To investigate whether antiphospholipid and related autoantibodies are
associated with IVF implantation failure as well as with recurrent spontaneous miscarriage …

Background Whether antibodies directed to β2-Glycoprotein I (aβ2GPI) are responsible for
LA activity is not well defined. However, in the absence of such antibodies the molecule …

Antiphospholipid syndrome (APS) is an autoimmune disorder in which antiphospholipid
antibodies (aPL) are thought to be involved in the development of venous and/or arterial …

Background The presence of lupus anticoagulant (LA) is an independent risk factor for
thrombosis. This laboratory phenomenon is detected as a phospholipid‐dependent …