Sodium citrate buffer improves pazopanib solubility and absorption in gastric acid-suppressed rat model
HJ Muhammad, T Shimada, A Fujita, Y Sai - Drug Metabolism and …, 2024 - Elsevier
Pazopanib exhibits pH-dependent solubility and its absorption depends primarily on the
stomach pH. Significant decrease of pazopanib absorption by coadministration with proton …
stomach pH. Significant decrease of pazopanib absorption by coadministration with proton …
[HTML][HTML] Deleterious association between proton pump inhibitor and protein kinase inhibitor exposure and survival for patients with lung cancer: A nationwide cohort …
C Bordet, M Zureik, Y Zelmat, M Lafaurie… - Cancer Treatment and …, 2024 - Elsevier
Introduction Previous studies have identified an interaction between protein kinase inhibitors
(PKIs) and proton pump inhibitors (PPIs) in patients with lung cancer. This type of interaction …
(PKIs) and proton pump inhibitors (PPIs) in patients with lung cancer. This type of interaction …