Amyloid β oligomers in Alzheimer's disease pathogenesis, treatment, and diagnosis

KL Viola, WL Klein - Acta neuropathologica, 2015 - Springer
Protein aggregation is common to dozens of diseases including prionoses, diabetes,
Parkinson's and Alzheimer's. Over the past 15 years, there has been a paradigm shift in …

[HTML][HTML] Curcumin's nanomedicine formulations for therapeutic application in neurological diseases

B Salehi, D Calina, AO Docea, N Koirala… - Journal of Clinical …, 2020 - mdpi.com
The brain is the body's control center, so when a disease affects it, the outcomes are
devastating. Alzheimer's and Parkinson's disease, and multiple sclerosis are brain diseases …

The mechanisms of action of curcumin in Alzheimer's disease

M Tang, C Taghibiglou - Journal of Alzheimer's disease, 2017 - content.iospress.com
Alzheimer's disease (AD) is a neurodegenerative disorder of the elderly. As the prevalence
of AD rises in the 21st century, there is an urgent need for the development of effective …

[HTML][HTML] New promising therapeutic avenues of curcumin in brain diseases

T Benameur, G Giacomucci, MA Panaro, M Ruggiero… - Molecules, 2021 - mdpi.com
Curcumin, the dietary polyphenol isolated from Curcuma longa (turmeric), is commonly used
as an herb and spice worldwide. Because of its bio-pharmacological effects curcumin is also …

Recent development of multifunctional agents as potential drug candidates for the treatment of Alzheimer's disease

N Guzior, A Wieckowska, D Panek… - Current medicinal …, 2015 - ingentaconnect.com
Alzheimer's disease (AD) is a complex and progressive neurodegenerative disorder. The
available therapy is limited to the symptomatic treatment and its efficacy remains …

Curcumin attenuates amyloid-β aggregate toxicity and modulates amyloid-β aggregation pathway

A Thapa, SD Jett, EY Chi - ACS chemical neuroscience, 2016 - ACS Publications
The abnormal misfolding and aggregation of amyloid-β (Aβ) peptides into β-sheet enriched
insoluble deposits initiates a cascade of events leading to pathological processes and …

Effects of oral curcumin ingested before or after eccentric exercise on markers of muscle damage and inflammation

Y Tanabe, K Chino, T Ohnishi, H Ozawa… - … Journal of Medicine …, 2019 - Wiley Online Library
We examined the effect of curcumin (CUR) ingestion before or after exercise on changes in
muscle damage and inflammatory responses after exercise. We conducted two parallel …

Evaluation of imidacloprid-induced neurotoxicity in male rats: a protective effect of curcumin

M Lonare, M Kumar, S Raut, P Badgujar… - Neurochemistry …, 2014 - Elsevier
The present study was carried out to evaluate the neurotoxic effect and biochemical
alteration as a result of imidacloprid (IMI) exposure and potential protective role of curcumin …

Effective timing of curcumin ingestion to attenuate eccentric exercise-induced muscle soreness in men

Y Tanabe, K Chino, H Sagayama, HJ Lee… - Journal of nutritional …, 2019 - jstage.jst.go.jp
Curcumin is known to have potent anti-inflammatory effects. We have reported that acute
curcumin ingestion attenuates eccentric exercise–induced muscle damage. This study …

Curcumin: A small molecule with big functionality against amyloid aggregation in neurodegenerative diseases and type 2 diabetes

S Radbakhsh, GE Barreto, AR Bland, A Sahebkar - Biofactors, 2021 - Wiley Online Library
Amyloidosis is a concept that implicates disorders and complications that are due to
abnormal protein accumulation in different cells and tissues. Protein aggregation …