[HTML][HTML] Metformin: Is it a drug for all reasons and diseases?

CR Triggle, I Mohammed, K Bshesh, I Marei, K Ye… - Metabolism, 2022 - Elsevier
Metformin was first used to treat type 2 diabetes in the late 1950s and in 2022 remains the
first-choice drug used daily by approximately 150 million people. An accumulation of …

Diabetes and the COVID-19 pandemic

K Khunti, J Valabhji, S Misra - Diabetologia, 2023 - Springer
Almost immediately after the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) virus emerged, it was evident that people with chronic diseases, including diabetes, were …

COVID-19 and diabetes

AK Singh, K Khunti - Annual review of medicine, 2022 - annualreviews.org
The prevalence of diabetes in people with coronavirus disease 2019 (COVID-19), caused by
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has varied worldwide …

Prognostic value of elevated lactate dehydrogenase in patients with COVID-19: a systematic review and meta-analysis

JW Martha, A Wibowo, R Pranata - Postgraduate medical journal, 2022 - academic.oup.com
Purpose This meta-analysis aimed to evaluate the prognostic performance of elevated
lactate dehydrogenase (LDH) in patients with COVID-19. Methods A systematic literature …

Diabetes and COVID-19: The past, the present, and the future

R Pranata, J Henrina, WM Raffaello, S Lawrensia… - Metabolism, 2021 - Elsevier
Diabetes, one of the most prevalent chronic diseases in the world, is strongly associated
with a poor prognosis in COVID-19. Scrupulous blood sugar management is crucial, since …

Preadmission use of antidiabetic medications and mortality among patients with COVID-19 having type 2 diabetes: A meta-analysis

NN Nguyen, DS Ho, HS Nguyen, DKN Ho, HY Li… - Metabolism, 2022 - Elsevier
Background Diabetes is an independent predictor of poor outcomes in patients with COVID-
19. We compared the effects of the preadmission use of antidiabetic medications on the in …

Therapeutic potential of metformin in COVID-19: reasoning for its protective role

SM Samuel, E Varghese, D Büsselberg - Trends in microbiology, 2021 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections present with
increased disease severity and poor clinical outcomes in diabetic patients compared with …

Diabetes and coronavirus (SARS-CoV-2): Molecular mechanism of Metformin intervention and the scientific basis of drug repurposing

E Varghese, SM Samuel, A Liskova, P Kubatka… - PLoS …, 2021 - journals.plos.org
Coronavirus Disease 2019 (COVID-19), caused by a new strain of coronavirus called
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), was declared a …

Metformin for cardiovascular protection, inflammatory bowel disease, osteoporosis, periodontitis, polycystic ovarian syndrome, neurodegeneration, cancer …

M Ala, M Ala - ACS pharmacology & translational science, 2021 - ACS Publications
Diabetes is accompanied by several complications. Higher prevalence of cancers,
cardiovascular diseases, chronic kidney disease (CKD), obesity, osteoporosis, and …

Mortality risk of antidiabetic agents for type 2 diabetes with COVID-19: a systematic review and meta-analysis

C Kan, Y Zhang, F Han, Q Xu, T Ye, N Hou… - Frontiers in …, 2021 - frontiersin.org
Aims We conducted a systematic review and meta-analysis to assess various antidiabetic
agents' association with mortality in patients with type 2 diabetes (T2DM) who have …