Porphyromonas gingivalis, a gram-negative anaerobe, is a major etiological agent in the
initiation and progression of severe forms of periodontal disease. An opportunistic pathogen …

While classical studies on host-parasite interactions have considered a “virulence factor” to
be a molecule (s) that exerts a detrimental effect (that is, toxin) on a host cell, recent …

Emerging data on the consequences of the interactions between invasive oral bacteria and
host cells have provided new insights into the pathogenesis of periodontal disease. Indeed …

Cumulative evidence indicates that bacterial adherence to mucosal and tooth surfaces as
well as bacterial coaggregation are essential steps for colonization of various oral bacterial …

Porphyromonas gingivalis is one of the principal organisms associated with adult
periodontitis. Bacterial surface proteins such as fimbriae and gingipain hemagglutinin …

In order to assess the role of polyphosphate kinase (PPK) in the physiology of
Porphyromonas gingivalis, a ppk gene mutant, CW120, was constructed and characterized …

Background: The microbial florae in adult periodontitis lesions are comprised of anaerobic
rods with Porphyromonas gingivalis as one of the major components (Slots 1976; Slots …

Porphyromonas gingivalis, an oral bacterium, might play a role in the pathogenesis or
progression of adult periodontitis. In this study, we isolated from P. gingivalis a putative …

Background Porphyromonas gingivalis is a major pathogen and has a high detection rate in
periodontal disease. Fimbriae and hemagglutinin are expressed by P. gingivalis, and these …

The indigenous oral microflora and the host are normally in a state of equilibrium; however,
the introduction of a pathogen can result in innate and adaptive immune responses that …