[HTML][HTML] SARS-CoV-2 variant biology: immune escape, transmission and fitness
AM Carabelli, TP Peacock, LG Thorne… - Nature Reviews …, 2023 - nature.com
In late 2020, after circulating for almost a year in the human population, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited a major step change in its …
respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited a major step change in its …
[HTML][HTML] The SARS-CoV-2 nucleocapsid protein: its role in the viral life cycle, structure and functions, and use as a potential target in the development of vaccines and …
W Wu, Y Cheng, H Zhou, C Sun, S Zhang - Virology journal, 2023 - Springer
Abstract Coronavirus disease 2019 (COVID-19) continues to take a heavy toll on personal
health, healthcare systems, and economies around the globe. Scientists are expending …
health, healthcare systems, and economies around the globe. Scientists are expending …
[HTML][HTML] SARS-CoV-2 breakthrough infections elicit potent, broad, and durable neutralizing antibody responses
Although infections among vaccinated individuals lead to milder COVID-19 symptoms
relative to those in unvaccinated subjects, the specificity and durability of antibody …
relative to those in unvaccinated subjects, the specificity and durability of antibody …
Analysis of 6.4 million SARS-CoV-2 genomes identifies mutations associated with fitness
Repeated emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variants with increased fitness underscores the value of rapid detection and characterization …
variants with increased fitness underscores the value of rapid detection and characterization …
Omicron mutations enhance infectivity and reduce antibody neutralization of SARS-CoV-2 virus-like particles
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant
contains extensive sequence changes relative to the earlier-arising B. 1, B. 1.1, and Delta …
contains extensive sequence changes relative to the earlier-arising B. 1, B. 1.1, and Delta …
[HTML][HTML] Neutralizing immunity in vaccine breakthrough infections from the SARS-CoV-2 Omicron and Delta variants
V Servellita, AM Syed, MK Morris, N Brazer, P Saldhi… - Cell, 2022 - cell.com
Virus-like particle (VLP) and live virus assays were used to investigate neutralizing immunity
against Delta and Omicron SARS-CoV-2 variants in 259 samples from 128 vaccinated …
against Delta and Omicron SARS-CoV-2 variants in 259 samples from 128 vaccinated …
[HTML][HTML] SARS-CoV-2 Omicron BA. 5: Evolving tropism and evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral …
A Aggarwal, A Akerman, V Milogiannakis, MR Silva… - …, 2022 - thelancet.com
Background Genetically distinct viral variants of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) have been recorded since January 2020. The introduction of …
coronavirus 2 (SARS-CoV-2) have been recorded since January 2020. The introduction of …
[HTML][HTML] An early warning system for emerging SARS-CoV-2 variants
An early warning system for emerging SARS-CoV-2 variants | Nature Medicine Skip to main
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[HTML][HTML] Molecular characteristics, immune evasion, and impact of SARS-CoV-2 variants
The persistent COVID-19 pandemic since 2020 has brought an enormous public health
burden to the global society and is accompanied by various evolution of the virus genome …
burden to the global society and is accompanied by various evolution of the virus genome …
Fitness effects of mutations to SARS-CoV-2 proteins
Abstract Knowledge of the fitness effects of mutations to SARS-CoV-2 can inform
assessment of new variants, design of therapeutics resistant to escape, and understanding …
assessment of new variants, design of therapeutics resistant to escape, and understanding …