[HTML][HTML] Structural and biological engineering of 3D hydrogels for wound healing

MH Norahan, SC Pedroza-González… - Bioactive materials, 2023 - Elsevier
Chronic wounds have become one of the most important issues for healthcare systems and
are a leading cause of death worldwide. Wound dressings are necessary to facilitate wound …

Tumor microenvironment: Challenges and opportunities in targeting metastasis of triple negative breast cancer

KGK Deepak, R Vempati, GP Nagaraju… - Pharmacological …, 2020 - Elsevier
Triple negative breast cancer (TNBC) is most aggressive subtype of breast cancers with high
probability of metastasis as well as lack of specific targets and targeted therapeutics. TNBC …

Tissue‐derived extracellular vesicles in cancers and non‐cancer diseases: present and future

SR Li, QW Man, X Gao, H Lin, J Wang… - Journal of …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are lipid‐bilayer membrane structures secreted by most cell
types. EVs act as messengers via the horizontal transfer of lipids, proteins, and nucleic …

Engineering exosomes as refined biological nanoplatforms for drug delivery

X Luan, K Sansanaphongpricha, I Myers… - Acta Pharmacologica …, 2017 - nature.com
Exosomes, a subgroup of extracellular vesicles (EVs), have been recognized as important
mediators of long distance intercellular communication and are involved in a diverse range …

Human mesenchymal stem cell derived exosomes enhance cell‐free bone regeneration by altering their miRNAs profiles

M Zhai, Y Zhu, M Yang, C Mao - Advanced Science, 2020 - Wiley Online Library
Implantation of stem cells for tissue regeneration faces significant challenges such as
immune rejection and teratoma formation. Cell‐free tissue regeneration thus has a potential …

Biomarkers in stress related diseases/disorders: diagnostic, prognostic, and therapeutic values

K Dhama, SK Latheef, M Dadar, HA Samad… - Frontiers in molecular …, 2019 - frontiersin.org
Various internal and external factors negatively affect the homeostatic equilibrium of
organisms at the molecular to the whole-body level, inducing the so-called state of stress …

Human mesenchymal stem cell derived exosomes alleviate type 2 diabetes mellitus by reversing peripheral insulin resistance and relieving β-cell destruction

Y Sun, H Shi, S Yin, C Ji, X Zhang, B Zhang, P Wu… - ACS …, 2018 - ACS Publications
Exosomes are nanosized extracellular vesicles (EVs) that show great promise in tissue
regeneration and injury repair as mesenchymal stem cell (MSC). MSC has been shown to …

Exosomes derived from human adipose mensenchymal stem cells accelerates cutaneous wound healing via optimizing the characteristics of fibroblasts

LI Hu, J Wang, X Zhou, Z Xiong, J Zhao, R Yu… - Scientific reports, 2016 - nature.com
Prolonged healing and scar formation are two major challenges in the treatment of soft
tissue trauma. Adipose mesenchymal stem cells (ASCs) play an important role in tissue …

Mesenchymal stem cell-derived extracellular vesicles as mediators of anti-inflammatory effects: endorsement of macrophage polarization

C Lo Sicco, D Reverberi, C Balbi, V Ulivi… - Stem cells …, 2017 - academic.oup.com
Abstract Mesenchymal Stem Cells (MSCs) are effective therapeutic agents enhancing the
repair of injured tissues mostly through their paracrine activity. Increasing evidences show …

Exosomes secreted by mesenchymal stem cells promote endothelial cell angiogenesis by transferring miR-125a

X Liang, L Zhang, S Wang, Q Han… - Journal of cell …, 2016 - journals.biologists.com
Angiogenesis plays crucial roles in various physiological processes including wound
healing and tissue repair. It requires a tight interaction between endothelial cells and their …