Accumulating evidence points to the causal role of triglyceride-rich lipoproteins and their
cholesterol-enriched remnants in atherogenesis. Genetic studies in particular have not only …

Aging and metabolism are inextricably linked, and many age-related changes in body
composition, including increased central adiposity and sarcopenia, have underpinnings in …

Accumulating clinical evidence has suggested serum triglyceride (TG) is a leading predictor
of atherosclerotic cardiovascular disease, comparable to low-density lipoprotein (LDL) …

Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality for
patients with type 2 diabetes, despite recent significant advances in management strategies …

There is a constant high demand for energy to sustain the continuous contractile activity of
the heart, which is met primarily by the β-oxidation of long-chain fatty acids. The control of …

The metabolic syndrome is a common metabolic disorder that results from the increasing
prevalence of obesity. The disorder is defined in various ways, but in the near future a new …

Visceral adipose tissue (VAT) is an important risk factor for obesity-related metabolic
disorders. Therefore, a reduction in VAT has become a key goal in obesity management …

The primary genetic, environmental, and metabolic factors responsible for causing insulin
resistance and pancreatic β-cell failure and the precise sequence of events leading to the …

Context An upper body/visceral fat distribution in obesity is closely linked with metabolic
complications, whereas increased lower body fat is independently predictive of reduced …

Insulin resistance is a key feature of the metabolic syndrome and often progresses to type 2
diabetes. Both insulin resistance and type 2 diabetes are characterized by dyslipidemia …