The human T cell leukemia virus type 1 (HTVL-1), first reported in 1980 by Robert Gallo's
group, is the etiologic agent of both cancer and inflammatory diseases. Despite …

MCL-1 is the prosurvival member of the Bcl-2 family. It prevents the induction of
mitochondria-dependent apoptosis. The molecular mechanisms dictating the host cell …

The transient depletion of monocytes alone prior to exposure of macaques to HTLV-1
enhances both HTLV-1WT (wild type) and HTLV-1p12KO (Orf-1 knockout) infectivity, but …

Human T-cell Leukemia virus type-1 (HTLV-1) causes adult T-cell leukemia/lymphoma
(ATLL), HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and other …

To gain insight into the origin, evolution, dissemination and viral factors affecting HTLV-1-
associated diseases, knowing the complete viral genome sequences is important. So far, no …

Background Primate T-lymphotropic viruses type 1 (PTLV-1) are complex retroviruses
infecting both human (HTLV-1) and simian (STLV-1) hosts. They share common …

The HTLV-1 is the first human retrovirus and is associated with several clinical syndromes,
however, the pathogenesis of these clinical manifestations is still not fully understood …

The human T‐cell lymphotropic virus type‐1 (HTLV‐1) is associated with severe
pathologies, such as HTLV‐1‐associated myelopathy/tropical spastic paraparesis …

The human T cell lymphotropic virus type 1 (HTLV-1) infects 5 to 10 million individuals and
remains without specific treatment. This retrovirus genome is composed of the genes gag …

Human T-lymphotropic virus type 1 (HTLV-1) was the first human retrovirus described. The
viral factors involved in the different clinical manifestations of infected individuals are still …