Melatonin and ferroptosis: Mechanisms and therapeutic implications
D Zhang, X Jia, D Lin, J Ma - Biochemical Pharmacology, 2023 - Elsevier
Ferroptosis, a regulated form of cell death, is characterized by iron-dependent lipid
peroxidation leading to oxidative damage to cell membranes. Cell sensitivity to ferroptosis is …
peroxidation leading to oxidative damage to cell membranes. Cell sensitivity to ferroptosis is …
[HTML][HTML] Ferroptosis: a new hunter of hepatocellular carcinoma
Y Jiang, Y Yu, Z Pan, C Glandorff, M Sun - Cell Death Discovery, 2024 - nature.com
Ferroptosis is an iron ion-dependent, regulatory cell death modality driven by intracellular
lipid peroxidation that plays a key role in the development of HCC. Studies have shown that …
lipid peroxidation that plays a key role in the development of HCC. Studies have shown that …
Ironing out the role of ferroptosis in immunity
Ferroptosis is a type of regulated cell death that drives the pathophysiology of many
diseases. Oxidative stress is detectable in many types of regulated cell death, but only …
diseases. Oxidative stress is detectable in many types of regulated cell death, but only …
Ferroptosis inhibitors: past, present and future
L Zhang, YL Luo, Y Xiang, XY Bai, RR Qiang… - Frontiers in …, 2024 - frontiersin.org
Ferroptosis is a non-apoptotic mode of programmed cell death characterized by iron
dependence and lipid peroxidation. Since the ferroptosis was proposed, researchers have …
dependence and lipid peroxidation. Since the ferroptosis was proposed, researchers have …
[HTML][HTML] Butylated Hydroxytoluene (BHT) Protects SH-SY5Y Neuroblastoma Cells from Ferroptotic Cell Death: Insights from In Vitro and In Vivo Studies
P Faraji, A Borchert, S Ahmadian, H Kuhn - Antioxidants, 2024 - mdpi.com
Ferroptosis is a special kind of programmed cell death that has been implicated in the
pathogenesis of a large number of human diseases. It involves dysregulated intracellular …
pathogenesis of a large number of human diseases. It involves dysregulated intracellular …
Ferroptosis as a potential therapeutic target for age-related macular degeneration
D Liu, Z Liu, H Liao, ZS Chen, B Qin - Drug Discovery Today, 2024 - Elsevier
Cell death plays a crucial part in the process of age-related macular degeneration (AMD),
but its mechanisms remain elusive. Accumulating evidence suggests that ferroptosis, a …
but its mechanisms remain elusive. Accumulating evidence suggests that ferroptosis, a …
Discovery of Novel Ortho-Aminophenol Derivatives Targeting Lipid Peroxidation with Potent Antiferroptotic Activities
XH Sheng, LC Han, A Gong, XS Meng… - Journal of Medicinal …, 2024 - ACS Publications
The concept of ferroptosis inhibition has gained growing recognition as a promising
therapeutic strategy for addressing a wide range of diseases. Here, we present the …
therapeutic strategy for addressing a wide range of diseases. Here, we present the …
Cr (VI) induces ferroptosis in DF-1 cells by simultaneously perturbing iron homeostasis of ferritinophagy and mitophagy
K Song, X Liu, H Xu, M Li, Q Zheng, C Qi… - Science of The Total …, 2024 - Elsevier
Abstract Hexavalent chromium [Cr (VI)] is an environmental pollutant known for its strong
oxidizing and carcinogenic effects. However, its potential to induce ferroptosis in poultry …
oxidizing and carcinogenic effects. However, its potential to induce ferroptosis in poultry …
Ferrostatin-1 mitigates cellular damage in a ferroptosis-like environment in Caenorhabditis elegans
MR Ferreyra, VL Romero… - Toxicological …, 2024 - academic.oup.com
Although iron (Fe) is the most biologically abundant transition metal, it is highly toxic when it
accumulates as Fe2+, forming a labile Fe pool and favoring the Fenton reaction. This …
accumulates as Fe2+, forming a labile Fe pool and favoring the Fenton reaction. This …
TaoHe ChengQi decoction ameliorates sepsis-induced cardiac dysfunction through anti-ferroptosis via the Nrf2 pathway
S Lu, B Yang, Z Tan, H Wang, M Xie, W Jiang, J Huang… - Phytomedicine, 2024 - Elsevier
Background Sepsis-induced cardiac dysfunction (SICD) is a serious complication of sepsis
that is associated with increased mortality. Ferroptosis has been reported in the SICD …
that is associated with increased mortality. Ferroptosis has been reported in the SICD …