Ferroptosis: the emerging player in remodeling triple-negative breast cancer

J Li, D He, S Li, J Xiao, Z Zhu - Frontiers in Immunology, 2023 - frontiersin.org
Triple-negative breast cancer (TNBC) is a highly heterogeneous breast tumor type that is
highly malignant, invasive, and highly recurrent. Ferroptosis is a unique mode of …

RNA m6A methylation regulators in sepsis

L Zhu, H Zhang, X Zhang, L Xia - Molecular and Cellular Biochemistry, 2023 - Springer
Abstract N6-methyladenosine (m6A) modification is a class of epitope modifications that has
received significant attention in recent years, particularly in relation to its role in various …

The emerging, multifaceted role of WTAP in Cancer and Cancer Therapeutics

G Ju, J Lei, S Cai, S Liu, X Yin, C Peng - Cancers, 2023 - mdpi.com
Simple Summary N6-methyladenosine (m6A) modification is among the most common and
conservative RNA modifications in eukaryotes. The deposition of m6A on RNA is carried out …

[HTML][HTML] Insights into the role of N6-methyladenosine in ferroptosis

J Zhang, T Qiu, X Yao, X Sun - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Abstract N6-methyladenosine (m 6 A) methylation modification is one of the most prevalent
epigenetic modifications of eukaryotic RNA. m 6 A methylation is widely associated with …

m6A methylation modification and immune cell infiltration: implications for targeting the catalytic subunit m6A-METTL complex in gastrointestinal cancer …

C Peng, F Xiong, X Pu, Z Hu, Y Yang, X Qiao… - Frontiers in …, 2023 - frontiersin.org
N6-methyladenosine (m6A) methylation modification is a ubiquitous RNA modification
involved in the regulation of various cellular processes, including regulation of RNA stability …

[HTML][HTML] The role of N6-methyladenosine modification in rodent models of neuropathic pain: from the mechanism to therapeutic potential

L Wu, H Tang - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Neuropathic pain (NP) is a common chronic pain condition resulted from lesions or diseases
of somatosensory nervous system, but the pathogenesis remains unclear. A growing body of …

[HTML][HTML] PIWI-interacting RNA-17458 is oncogenic and a potential therapeutic target in cervical cancer

L Liu, L Li, W Zu, J Jing, G Liu, T Sun, Q Xie - Journal of Cancer, 2023 - ncbi.nlm.nih.gov
Cervical cancer (CC) is one of the leading cancers among the female reproductive system.
The piwi-interacting RNA (piRNA) function and biogenesis has been studied in various …

WTAP‐induced N6‐methyladenosine of PD‐L1 blocked T‐cell‐mediated antitumor activity under hypoxia in colorectal cancer

Q Liu, N Zhang, J Chen, M Zhou, D Zhou… - Cancer …, 2024 - Wiley Online Library
Abstract N 6‐Methyladenosine (m6A) is a important process regulating gene expression
post‐transcriptionally. Programmed death ligand 1 (PD‐L1) is a major immune inhibitive …

Targeting key RNA methylation enzymes to improve the outcome of colorectal cancer chemotherapy

C Shao, Y Han, Y Huang, Z Zhang… - International …, 2024 - spandidos-publications.com
RNA methylation modifications are closely linked to tumor development, migration, invasion
and responses to various therapies. Recent studies have shown notable advancements …

The lncRNAMALAT1-WTAP axis: a novel layer of EMT regulation in hypoxic triple-negative breast cancer

M Dragonetti, C Turco, A Benedetti, F Goeman… - Cell Death …, 2024 - nature.com
Early metastatic disease development is one characteristic that defines triple-negative
breast cancer (TNBC) as the most aggressive breast cancer (BC) subtype. Numerous …