The cholesterol-dependent cytolysins (CDCs) are a large family of pore-forming toxins that
are produced by more than 20 species from the genera Clostridium, Streptococcus, Listeria …

S treptococcus anginosus and the closely related species S treptococcus constellatus and S
treptococcus intermedius, are primarily commensals of the mucosa. The true pathogenic …

Cholesterol is believed to serve as the common receptor for the cholesterol-dependent
cytolysins (CDCs). One member of this toxin family, Streptococcus intermedius …

The distribution of intermedilysin, a human-specific cytolysin, among the anginosus group
streptococci and the correlation of toxin production and infection by Streptococcus …

Abstract Background The Streptococcus Anginosus Group (SAG) represents three closely
related species of the viridans group streptococci recognized as commensal bacteria of the …

Streptococcus intermedius causes endogenous infections leading to abscesses. This
species produces intermedilysin (ILY), a human‐specific cytolysin. Because of the significant …

Intermedilysin is a pore‐forming cytolysin belonging to the streptolysin O gene family known
as the 'Cholesterol‐binding/dependent cytolysins' and is unique within the family in that it is …

High-density lipoproteins (HDLs) are a group of different subpopulations of sialylated
particles that have an essential role in the reverse cholesterol transport (RCT) pathway …

Streptococcus intermedius is a member of the normal flora of the mouth but is also an
opportunistic pathogen associated with purulent infections at oral and nonoral sites …

US8128939B2 - Mutants of cholesterol-dependent cytolysins and uses thereof - Google
Patents US8128939B2 - Mutants of cholesterol-dependent cytolysins and uses thereof …