Background In non-small cell lung cancer (NSCLC), there may be a relationship between
programmed death-ligand 1 (PD-L1) expression, driver mutations and cigarette smoking …

Abstract Background ROS1 rearrangements (ROS1+) define a distinct molecular subset of
lung adenocarcinomas. ROS1+ tumors are known to occur more in never-smokers, but the …

Lung cancer is one of the most frequently diagnosed malignancies and is a widespread
disease that affects millions of individuals globally. CXCL17 is a member of the CXC …

With the rapid development of lung cancer molecular detection and precision therapy,
targeted therapy has covered the entire process of diagnosis and treatment of nonsmall cell …

Background The N6‐methyladenosine (m6A) can modify long non‐coding RNAs (lncRNAs),
thereby influencing a wide array of biological functions. However, the prognosis of m6A …

Avian pathogenic E. coli (APEC), one of the widespread zoonotic-pathogen, can cause a
series of diseases collectively known as colibacillosis. This disease can cause thousands of …

YAP1, a key mediator of the Hippo pathway, plays an important role in tumorigenesis.
Alternative splicing of human YAP1 mRNA results in two major isoforms: YAP1‐1, which …

Recent studies have shown that NOP2, a nucleolar protein, is up-regulated in various
cancers, suggesting a potential link to tumor aggressiveness and unfavorable outcomes …

背景与目的近年来, 程序性细胞死亡受体1 (programmed cell death 1, PD-
1)/程序性细胞死亡配体1 (programmed cell death ligand 1, PD-L1) 免疫抑制剂为代表的免疫 …

肺癌是全球最常见的恶性肿瘤， 也是癌症死亡的主要原因。 人表皮生长因子受体2（ human
epidermal growth factor receptor 2, HER2） 阳性非小细胞肺癌（ non-small cell lung cancer …