[HTML][HTML] Immune system gene polymorphisms associated with severe dengue in Latin America: a systematic review

JE Salazar Flórez, ÁM Segura Cardona… - Revista do Instituto de …, 2023 - SciELO Brasil
One of the main challenges in the clinical management of dengue is the early identification
of cases that could progress to severe forms of the disease. A biomarker that may enable …

Endothelial dysfunction, HMGB1, and dengue: an enigma to solve

MA Calderón-Peláez, C Coronel-Ruiz, JE Castellanos… - Viruses, 2022 - mdpi.com
Dengue is a viral infection caused by dengue virus (DENV), which has a significant impact
on public health worldwide. Although most infections are asymptomatic, a series of severe …

Population genetics-informed meta-analysis in seven genes associated with risk to dengue fever disease

M Oliveira, DP Saraiva, B Cavadas… - Infection, Genetics and …, 2018 - Elsevier
Population genetics theory predicted that rare frequent markers would be the main
contributors for heritability of complex diseases, but meta-analyses of genome-wide …

Cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4)+ 49A> G (rs231775) gene polymorphism is not associated with COVID-19 severity and mortality in an Iranian …

ES Mirsharif, A Rostamian, M Salehi, N Askari… - Heliyon, 2024 - cell.com
Introduction Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) regulates T cell immune
responses as an immune activation inhibitor. Literature reviews suggest that COVID-19 is …

Association between interferon lambda 3 rs12979860 polymorphism and clinical outcome in dengue virus‐infected children

RD da Silva Cezar… - International Journal …, 2020 - Wiley Online Library
Single nucleotide polymorphisms (SNPs) in immune‐related genes have been shown to
play a role in driving the development of the severe phenotypes of dengue virus (DENV) …

Impact of polymorphisms in genes orchestrating innate immune responses on replication kinetics of Torque teno virus after kidney transplantation

N Redondo, I Rodríguez-Goncer, P Parra… - Frontiers in …, 2022 - frontiersin.org
Background: Torque teno virus (TTV) DNAemia has been proposed as a surrogate marker of
immunosuppression after kidney transplantation (KT), under the assumption that the control …

The Genetic Variant TNFA (rs361525) Is Associated with Increased Susceptibility to Developing Dengue Symptoms

ME Villanueva-Aguilar, LC Rizo-de-la-Torre… - Viral …, 2023 - liebertpub.com
Dengue virus (DENV) is the causal agent of dengue fever. The symptoms and signs of
dengue vary from febrile illness to hemorrhagic syndrome. IFITM3 and TNFA are genes of …

Interferon-gamma gene diplotype (AA-rs2069716/AG-rs2069727) may play an important role during secondary outcomes of severe dengue in Brazilian patients

CC Bresani-Salvi, CNL Morais, HVPC Neco… - Revista do Instituto de …, 2023 - SciELO Brasil
Dengue is a global and growing health threat, especially in Southeast Asia, West Pacific and
South America. Infection by the dengue virus (DENV) results in dengue fever, which can …

Genetic association study of interferon lambda 3, CD27, and human leukocyte antigen-DPB1 with dengue severity in Thailand

U Arayasongsak, I Naka, J Ohashi… - BMC Infectious …, 2020 - Springer
Background Dengue patients develop different disease severity ranging from mild (dengue
fever [DF]) to severe forms (dengue hemorrhagic fever [DHF] and the fatal dengue shock …