Presynaptic membrane receptors in acetylcholine release modulation in the neuromuscular synapse

J Tomàs, MM Santafé, N Garcia… - Journal of …, 2014 - Wiley Online Library
Over the past few years, we have studied, in the mammalian neuromuscular junction (NMJ),
the local involvement in transmitter release of the presynaptic muscarinic ACh autoreceptors …

Transgenic overexpression of adenosine kinase in brain leads to multiple learning impairments and altered sensitivity to psychomimetic drugs

BK Yee, P Singer, JF Chen, J Feldon… - European Journal of …, 2007 - Wiley Online Library
The neuromodulator adenosine fulfills a unique role in the brain affecting glutamatergic
neurotransmission and dopaminergic signaling via activation of adenosine A1 and A2A …

In vitro pharmacological profile of the A2A receptor antagonist istradefylline

M Saki, K Yamada, E Koshimura, K Sasaki… - … archives of pharmacology, 2013 - Springer
Adenosine A 2A receptors are suggested to be a promising non-dopaminergic target for the
treatment of Parkinson's disease (PD). Istradefylline is an adenosine A 2A receptor …

A1 adenosine receptor activation induces ventriculomegaly and white matter loss

CP Turner, H Yan, M Schwartz, T Othman… - …, 2002 - journals.lww.com
A1 adenosine receptors (A1ARs) are widely expressed in the brain during development. To
examine whether A1AR activation can alter postnatal brain formation, neonatal rats from …

Adenosine augmentation therapies (AATs) for epilepsy: prospect of cell and gene therapies

D Boison - Epilepsy research, 2009 - Elsevier
Deficiencies in the brain's own adenosine-based seizure control system contribute to
seizure generation. Consequently, reconstitution of adenosinergic neuromodulation …

Modulation of short-term social memory in rats by adenosine A1 and A2A receptors

RDS Prediger, RN Takahashi - Neuroscience letters, 2005 - Elsevier
The recognition of an unfamiliar juvenile rat by an adult rat has been shown to imply short-
term memory processes. The present study was designed to examine the role of adenosine …

ADORA2A variation and adenosine A1 receptor availability in the human brain with a focus on anxiety-related brain regions: modulation by ADORA1 variation

C Hohoff, T Kroll, B Zhao, N Kerkenberg, I Lang… - Translational …, 2020 - nature.com
Adenosine, its interacting A1 and A2A receptors, and particularly the variant rs5751876 in
the A2A gene ADORA2A have been shown to modulate anxiety, arousal, and sleep. In a …

Behavioral recovery following sub-chronic paeoniflorin administration in the striatal 6-OHDA lesion rodent model of Parkinson's disease

DZ Liu, J Zhu, DZ Jin, LM Zhang, XQ Ji, Y Ye… - Journal of …, 2007 - Elsevier
In the present studies, the effect of paeoniflorin (PF), one of the main compounds extracted
from Paeoniae radix, in alleviating the neurological impairment following unilateral striatal 6 …

Adenosine A2A receptors enhance GABA transport into nerve terminals by restraining PKC inhibition of GAT‐1

S Cristóvão‐Ferreira, SH Vaz, JA Ribeiro… - Journal of …, 2009 - Wiley Online Library
Neurotransmitter transporters are regulated by phosphorylation but little is known about
endogenous substances and receptors that regulate this process. Adenosine is an …

Electroacupuncture at Zusanli and at Neiguan characterized point specificity in the brain by metabolomic analysis

DY Lee, YR Jiu, CL Hsieh - Scientific reports, 2020 - nature.com
Different point stimulations can induce brain activity in specific regions, and however
whether these stimulations affect unique neurotransmitter transmission remains unknown …