Mechanisms of cross-talk between G-protein-coupled receptors

Y Cordeaux, SJ Hill - Neurosignals, 2002 - karger.com
There is increasing evidence to suggest that 'cross-talk'occurs between G-protein-coupled
receptors and their intracellular second messenger pathways. Cross-talk between different …

Exploring the recognition pathway at the human A 2A adenosine receptor of the endogenous agonist adenosine using supervised molecular dynamics simulations

D Sabbadin, A Ciancetta, G Deganutti, A Cuzzolin… - …, 2015 - pubs.rsc.org
Adenosine is a naturally occurring purine nucleoside that exerts a variety of important
biological functions through the activation of four G protein-coupled receptor (GPCR) …

Electroacupuncture at Zusanli and at Neiguan characterized point specificity in the brain by metabolomic analysis

DY Lee, YR Jiu, CL Hsieh - Scientific reports, 2020 - nature.com
Different point stimulations can induce brain activity in specific regions, and however
whether these stimulations affect unique neurotransmitter transmission remains unknown …

Adenosine A2A receptors and their role in drug addiction

RM Brown, JL Short - Journal of Pharmacy and Pharmacology, 2008 - Wiley Online Library
The specific events between initial presumably manageable drug intake and the
development of a drug‐addicted state are not yet known. Drugs of abuse have varying …

Caffeine inhibition of rat carotid body chemoreceptors is mediated by A2A and A2B adenosine receptors

SV Conde, A Obeso, I Vicario, R Rigual… - Journal of …, 2006 - Wiley Online Library
Caffeine, an unspecific antagonist of adenosine receptors, is commonly used to treat the
apnea of prematurity. We have defined the effects of caffeine on the carotid body (CB) …

Migraine and sleep in children: a bidirectional relationship

IM Pavkovic, SV Kothare - Pediatric neurology, 2020 - Elsevier
Migraine and sleep disorders in children exhibit a bidirectional relationship. This
relationship is based on shared pathophysiology. Migraine involves activation of the …

P2Y13 receptors mediate presynaptic inhibition of acetylcholine release induced by adenine nucleotides at the mouse neuromuscular junction

JF Guarracino, AR Cinalli, V Fernández, LI Roquel… - Neuroscience, 2016 - Elsevier
It is known that adenosine 5′-triphosphate (ATP) is released along with the
neurotransmitter acetylcholine (ACh) from motor nerve terminals. At mammalian …

Adenosine actions on oligodendroglia and myelination in autism spectrum disorder

HY Shen, N Huang, J Reemmer, L Xiao - Frontiers in Cellular …, 2018 - frontiersin.org
Autism spectrum disorder (ASD) is the most commonly diagnosed neurodevelopmental
disorder. Independent of neuronal dysfunction, ASD and its associated comorbidities have …

[HTML][HTML] Adenosine A1 and A2A receptors of hippocampal CA1 region have opposite effects on piriform cortex kindled seizures in rats

M Zeraati, J Mirnajafi-Zadeh, Y Fathollahi, S Namvar… - Seizure, 2006 - Elsevier
In this study the role of adenosine A1 and A2A receptors of the hippocampal CA1 region on
piriform cortex-kindled seizures was investigated in rats. Animals were kindled by daily …

Modulation of seizures and synaptic plasticity by adenosinergic receptors in an experimental model of temporal lobe epilepsy induced by pilocarpine in rats

EPM Vianna, AT Ferreira, F Doná, EA Cavalheiro… - …, 2005 - Wiley Online Library
Purpose: Adenosine is a major negative neuromodulator of synaptic activity in the central
nervous system and can exert anticonvulsant and neuroprotective effects in many …