Causes and consequences of oxidative stress in spermatozoa

RJ Aitken, Z Gibb, MA Baker, J Drevet… - Reproduction, Fertility …, 2016 - CSIRO Publishing
Spermatozoa are highly vulnerable to oxidative attack because they lack significant
antioxidant protection due to the limited volume and restricted distribution of cytoplasmic …

[HTML][HTML] Male subfertility and oxidative stress

EPP Evans, JTM Scholten, A Mzyk… - Redox biology, 2021 - Elsevier
To date 15% of couples are suffering from infertility with 45–50% of males being
responsible. With an increase in paternal age as well as various environmental and lifestyle …

Melatonin protects mouse testes from palmitic acid‐induced lipotoxicity by attenuating oxidative stress and DNA damage in a SIRT1‐dependent manner

D Xu, L Liu, Y Zhao, L Yang, J Cheng… - Journal of pineal …, 2020 - Wiley Online Library
Palmitic acid (PA), the main component of dietary saturated fat, has been known to increase
in patients with obesity, and PA‐induced lipotoxicity may contribute to obesity‐related male …

Sperm DNA damage caused by oxidative stress: modifiable clinical, lifestyle and nutritional factors in male infertility

C Wright, S Milne, H Leeson - Reproductive biomedicine online, 2014 - Elsevier
DNA fragmentation is an important factor in the aetiology of male infertility. However, it is still
underevaluated and its inclusion in routine semen analysis is debated. DNA fragmentation …

Mitochondria: their role in spermatozoa and in male infertility

M Boguenet, PE Bouet, A Spiers… - Human …, 2021 - academic.oup.com
BACKGROUND The best-known role of spermatozoa is to fertilize the oocyte and to transmit
the paternal genome to offspring. These highly specialized cells have a unique structure …

Oxidative stress and male infertility—a clinical perspective

K Tremellen - Human reproduction update, 2008 - academic.oup.com
Oxidative stress occurs when the production of potentially destructive reactive oxygen
species (ROS) exceeds the bodies own natural antioxidant defenses, resulting in cellular …

The role of sperm oxidative stress in male infertility and the significance of oral antioxidant therapy

P Gharagozloo, RJ Aitken - Human reproduction, 2011 - academic.oup.com
Oxidative stress in the male germ line is thought to affect male fertility and impact upon
normal embryonic development. Accordingly, fertility specialists are actively exploring the …

[HTML][HTML] Impact of cryopreservation on spermatozoa freeze-thawed traits and relevance OMICS to assess sperm cryo-tolerance in farm animals

IM Khan, Z Cao, H Liu, A Khan, SU Rahman… - Frontiers in Veterinary …, 2021 - frontiersin.org
Sperm cryopreservation is a powerful tool for the livestock breeding program. Several
technical attempts have been made to enhance the efficiency of spermatozoa …

Oxidative stress & male infertility

K Makker, A Agarwal, R Sharma - Indian Journal of Medical …, 2009 - journals.lww.com
The male factor is considered a major contributory factor to infertility. Apart from the
conventional causes for male infertility such as varicocoele, cryptorchidism, infections …

Clinical relevance of oxidative stress in male factor infertility: an update

A Agarwal, K Makker, R Sharma - American journal of …, 2008 - Wiley Online Library
Male factor has been considered a major contributory factor to infertility. Along with the
conventional causes for male infertility such as varicocele, cryptorchidism, infections …