The sympathetic nervous system (SNS) has a critical role in continuously coordinating
responses to stimuli internal and external to the human body by appropriately modulating …

The cerebral vasculature manages oxygen delivery by adjusting arterial blood in‐flow in the
face of reductions in oxygen availability. Hypoxic cerebral vasodilatation, and the associated …

Key points It is unknown whether excessive reactive oxygen species (ROS) production
drives the isocapnic hyperoxia (IH)‐induced decline in human cerebral blood flow (CBF) via …

Poor maternal nutrition during pregnancy is known to impair fetal development. Moreover,
the preimplantation period is vulnerable to adverse programming of disease. Here, we …

Key points ATP‐sensitive K+ (KATP) channels mediate hypoxia‐induced cerebral
vasodilatation and hyperperfusion in animals. We tested whether KATP channels blockade …

In hypertension, the cardiorespiratory responses to peripheral chemoreflex activation
(hypoxia) and inactivation (hyperoxia) are reportedly augmented, but the impact on …

In animals, the blockade of acid-sensing ion channels (ASICs), cation pore-forming
membrane proteins located in the free nerve endings of group IV afferent fibers, attenuates …

Introduction Little is known about the systemic and pulmonary macrohemodynamics in early
COVID‐19 infection. Echocardiography may provide useful insights into COVID‐19 …

Key points The activation of the group III/IV skeletal muscle afferents is one of the principal
mediators of cardiovascular responses to exercise; however, the neuronal circuitry …

Key points The proposed mechanism for the increased ventilation in response to hyperoxia
includes a reduced brain CO2–[H+] washout‐induced central chemoreceptor stimulation …