Pituitary adenomas are considered benign tumors, but approximately 10% of them can have
an aggressive behavior and more rarely (0.2%) can present metastasis, being classified as …

A subset of pituitary neuroendocrine tumors (PitNETs) have an aggressive behavior,
showing resistance to treatment and/or multiple recurrences in spite of the optimal use of …

The use of temozolomide (TMZ) for the management of aggressive pituitary tumours (APT)
has revolutionised clinical practice in this field with significantly improved clinical outcomes …

The long noncoding RNA growth arrest-specific transcript 5 (GAS5) has been reported to
function as a suppressor in many cancers. However, the role and mechanism of lncRNA …

The hypothalamic neuroendocrine catecholamine dopamine regulates the lactotroph
function, including prolactin (PRL) secretion, proliferation, and apoptosis. The treatment of …

Zusammenfassung Hintergrund Der vorliegende Beitrag befasst sich mit den häufigsten
Hypophysentumoren sowie den diversen Differenzialdiagnosen. Dabei liegt der …

Background: Infiltration is important for the surgical planning and prognosis of pituitary
adenomas. Differences in preoperative diagnosis have been noted. The aim of this article is …

Somatic GNAS and USP8 mutations have been implicated in sporadic somatotrophinomas
and corticotrophinomas, respectively. However, no genes are known to be recurrently …

Simple Summary Many studies have demonstrated that the antagonists of growth hormone-
releasing hormone (GHRH) exert inhibitory activities in a variety of experimental cancers; …

Significant advances in genomics and molecular genetics in recent years have reshaped the
practice of endocrine pathology. Pan-genomic studies, including the pioneering ones on …