Genetically encoded voltage indicators

I Mollinedo-Gajate, C Song, T Knöpfel - Optogenetics: Light-Sensing …, 2021 - Springer
Optogenetic approaches combine the power to allocate optogenetic tools (proteins) to
specific cell populations (defined genetically or functionally) and the use of light-based …

All-optical electrophysiology in behaving animals

Y Adam - Journal of Neuroscience Methods, 2021 - Elsevier
Technology for simultaneous control and readout of the membrane potential of multiple
neurons in behaving animals at high spatio-temporal resolution will have a high impact on …

Evaluation of compact pulsed lasers for two-photon microscopy using a simple method for measuring two-photon excitation efficiency

S Saidi, M Shtrahman - Neurophotonics, 2023 - spiedigitallibrary.org
Significance Two-photon (2p) microscopy has historically relied on titanium sapphire pulsed
lasers that are expensive and have a large footprint. Recently, several manufacturers have …

Low-light photodetectors for fluorescence microscopy

H Yokota, A Fukasawa, M Hirano, T Ide - Applied Sciences, 2021 - mdpi.com
Over the years, fluorescence microscopy has evolved and has become a necessary element
of life science studies. Microscopy has elucidated biological processes in live cells and …

Light-field microscopy for fast volumetric brain imaging

Z Zhang, L Cong, L Bai, K Wang - Journal of Neuroscience Methods, 2021 - Elsevier
Recording neural activities over large populations is critical for a better understanding of the
functional mechanisms of animal brains. Traditional optical imaging technologies for in vivo …

Energy-efficient LSTM inference accelerator for real-time causal prediction

Z Chen, HT Blair, J Cong - ACM Transactions on Design Automation of …, 2022 - dl.acm.org
Ever-growing edge applications often require short processing latency and high energy
efficiency to meet strict timing and power budget. In this work, we propose that the compact …

Two-photon Bessel beam tomography for fast volume imaging

AF Valle, JD Seelig - Optics express, 2019 - opg.optica.org
Light microscopy on dynamic samples, for example neural activity in the brain, often requires
imaging volumes that extend over several 100 µm in axial direction at a rate of at least …

Advantages, Pitfalls, and Developments of All Optical Interrogation Strategies of Microcircuits in vivo

S Papaioannou, P Medini - Frontiers in neuroscience, 2022 - frontiersin.org
The holy grail for every neurophysiologist is to conclude a causal relationship between an
elementary behaviour and the function of a specific brain area or circuit. Our effort to map …

Modified phase-offset-driven Lissajous scanning endomicroscopy with a polyimide-film-based frequency separator

J Im, Y Chang, C Song - IEEE/ASME Transactions on …, 2022 - ieeexplore.ieee.org
This article presents a Lissajous scanning confocal endomicroscopy comprising an easily
manufacturable thin polyimide (PI) film and modified phase-offset-driven scanning. The …

BLINK: bit-sparse LSTM inference kernel enabling efficient calcium trace extraction for neurofeedback devices

Z Chen, GJ Blair, HT Blair, J Cong - Proceedings of the ACM/IEEE …, 2020 - dl.acm.org
Miniaturized fluorescent calcium imaging microscopes are widely used for monitoring the
activity of a large population of neurons in freely behaving animals in vivo. Conventional …