What makes a megaplasmid?

JPJ Hall, J Botelho, A Cazares… - … Transactions of the …, 2022 - royalsocietypublishing.org
Naturally occurring plasmids come in different sizes. The smallest are less than a kilobase of
DNA, while the largest can be over three orders of magnitude larger. Historically, research …

[HTML][HTML] Worldwide Dissemination of blaKPC Gene by Novel Mobilization Platforms in Pseudomonas aeruginosa: A Systematic Review

D Forero-Hurtado, ZL Corredor-Rozo… - Antibiotics, 2023 - mdpi.com
The dissemination of bla KPC-harboring Pseudomonas aeruginosa (KPC-Pa) is considered
a serious public health problem. This study provides an overview of the epidemiology of …

Emergence of ceftazidime-and avibactam-resistant Klebsiella pneumoniae carbapenemase-producing Pseudomonas aeruginosa in China

Y Zhu, J Chen, H Shen, Z Chen, Q Yang, J Zhu, X Li… - Msystems, 2021 - Am Soc Microbiol
Klebsiella pneumoniae carbapenemase (KPC)-producing Pseudomonas aeruginosa (KPC-
PA) has been reported sporadically. However, epidemiological and antimicrobial …

Microbial silver resistance mechanisms: Recent developments

E Terzioğlu, M Arslan, BG Balaban… - World Journal of …, 2022 - Springer
In this mini-review, after a brief introduction into the widespread antimicrobial use of silver
ions and nanoparticles against bacteria, fungi and viruses, the toxicity of silver compounds …

Antimicrobial coatings for environmental surfaces in hospitals: a potential new pillar for prevention strategies in hygiene

W Bäumler, D Eckl, T Holzmann… - Critical Reviews in …, 2022 - Taylor & Francis
Recent reports provide evidence that contaminated healthcare environments represent
major sources for the acquisition and transmission of pathogens. Antimicrobial coatings …

Epidemic territorial spread of IncP-2-type VIM-2 carbapenemase-encoding megaplasmids in nosocomial Pseudomonas aeruginosa populations

P Urbanowicz, I Bitar, R Izdebski… - Antimicrobial agents …, 2021 - Am Soc Microbiol
In 2003 to 2004, the first five VIM-2 metallo-β-lactamase (MBL)-producing Pseudomonas
aeruginosa (MPPA) isolates with an In4-like integron, In461 (aadB-bla VIM-2-aadA6), on …

[HTML][HTML] Prioritization of Critical Factors for Surveillance of the Dissemination of Antibiotic Resistance in Pseudomonas aeruginosa: A Systematic Review

JH Lee, NH Kim, KM Jang, H Jin, K Shin… - International Journal of …, 2023 - mdpi.com
Pseudomonas aeruginosa is the primary opportunistic human pathogen responsible for a
range of acute and chronic infections; it poses a significant threat to immunocompromised …

High-level expression of cell-surface signaling system Hxu enhances Pseudomonas aeruginosa bloodstream infection

F Yang, Y Zhou, P Chen, Z Cai, Z Yue, Y Jin… - Infection and …, 2022 - Am Soc Microbiol
Bloodstream infections (BSIs) caused by Pseudomonas aeruginosa are associated with a
high mortality rate in the clinic. However, the fitness mechanisms responsible for the …

[HTML][HTML] Characterization of β-lactamase and virulence genes in Pseudomonas aeruginosa isolated from clinical, environmental and poultry sources in Bangladesh

R Islam, FB Ferdous, MN Hoque, NA Asif, ML Rana… - Plos one, 2024 - journals.plos.org
The emergence and spread of multidrug-resistant pathogens like Pseudomonas aeruginosa
are major concerns for public health worldwide. This study aimed to assess the prevalence …

An XDR Pseudomonas aeruginosa ST463 Strain with an IncP-2 Plasmid Containing a Novel Transposon Tn6485f Encoding blaIMP-45 and blaAFM-1 and a Second Plasmid with Two …

Y Fang, N Wang, Z Wu, Y Zhu, Y Ma, Y Li… - Microbiology …, 2023 - Am Soc Microbiol
The increased carbapenem resistance among Pseudomonas aeruginosa has become a
serious health issue worldwide. We reported an extensively drug-resistant (XDR) P …