Screening for colorectal cancer is widespread and successful, but screening programs
across the globe differ in their recommendations. In this review article, Helsingen and …

The chances of survival for a patient with cancer are substantially improved if the disease is
diagnosed and treated at an early clinical stage (1). This underpins the promise of early …

Background Instead of a single value for mammographic sensitivity, a sensitivity function
based on tumor size more realistically reflects mammography's detection capability …

Background & Aims We investigated whether 2 quantitative fecal immunochemical tests
(FITs) with the same cutoff concentration of fecal hemoglobin perform equivalently in …

Purpose: This study aimed to quantify the probability of overdiagnosis of prostate cancer by
polygenic risk. Methods: We calculated the polygenic risk score based on 66 known prostate …

We examine the theoretical basis of screening, followed by an evaluation of screening
initiatives from a population health perspective and a discussion of the organisation of mass …

Novel liquid biopsy technologies are creating a watershed moment in cancer early
detection. Evidence supporting population screening is nascent, but a rush to market the …

We compared test sensitivity (in terms of prevented cancers) and overdiagnosis (in terms of
non‐progressive pre‐invasive lesions) between the human papillomavirus test (HPV test …

The interval colorectal cancer (CRC) rate after negative fecal immunochemical testing (FIT)
is an important quality indicator of CRC screening programs. We analyzed the outcomes of …

Objectives To report the sensitivities of the faecal occult blood test, screening episode, and
screening programme for colorectal cancer and the benefits of applying a randomised …