Colorectal cancer screening—approach, evidence, and future directions
LM Helsingen, M Kalager - NEJM evidence, 2022 - evidence.nejm.org
Screening for colorectal cancer is widespread and successful, but screening programs
across the globe differ in their recommendations. In this review article, Helsingen and …
across the globe differ in their recommendations. In this review article, Helsingen and …
The challenge of early detection in cancer
N Pashayan, PDP Pharoah - Science, 2020 - science.org
The chances of survival for a patient with cancer are substantially improved if the disease is
diagnosed and treated at an early clinical stage (1). This underpins the promise of early …
diagnosed and treated at an early clinical stage (1). This underpins the promise of early …
[HTML][HTML] Mammographic sensitivity as a function of tumor size: A novel estimation based on population-based screening data
Background Instead of a single value for mammographic sensitivity, a sensitivity function
based on tumor size more realistically reflects mammography's detection capability …
based on tumor size more realistically reflects mammography's detection capability …
[HTML][HTML] Difference in performance of fecal immunochemical tests with the same hemoglobin cutoff concentration in a nationwide colorectal cancer screening program
TH Chiang, SL Chuang, SLS Chen, HM Chiu, AMF Yen… - Gastroenterology, 2014 - Elsevier
Background & Aims We investigated whether 2 quantitative fecal immunochemical tests
(FITs) with the same cutoff concentration of fecal hemoglobin perform equivalently in …
(FITs) with the same cutoff concentration of fecal hemoglobin perform equivalently in …
Implications of polygenic risk-stratified screening for prostate cancer on overdiagnosis
Purpose: This study aimed to quantify the probability of overdiagnosis of prostate cancer by
polygenic risk. Methods: We calculated the polygenic risk score based on 66 known prostate …
polygenic risk. Methods: We calculated the polygenic risk score based on 66 known prostate …
Cancer screening: evidence and practice in Europe 2008
M Hakama, MP Coleman, DM Alexe… - European Journal of …, 2008 - Elsevier
We examine the theoretical basis of screening, followed by an evaluation of screening
initiatives from a population health perspective and a discussion of the organisation of mass …
initiatives from a population health perspective and a discussion of the organisation of mass …
Revisiting the standard blueprint for biomarker development to address emerging cancer early detection technologies
Novel liquid biopsy technologies are creating a watershed moment in cancer early
detection. Evidence supporting population screening is nascent, but a rush to market the …
detection. Evidence supporting population screening is nascent, but a rush to market the …
The HPV test has similar sensitivity but more overdiagnosis than the Pap test—a randomised health services study on cervical cancer screening in Finland
N Malila, M Leinonen… - … Journal of Cancer, 2013 - Wiley Online Library
We compared test sensitivity (in terms of prevented cancers) and overdiagnosis (in terms of
non‐progressive pre‐invasive lesions) between the human papillomavirus test (HPV test …
non‐progressive pre‐invasive lesions) between the human papillomavirus test (HPV test …
Factors associated with interval colorectal cancer after negative FIT: Results of two screening rounds in the Dutch FIT‐based CRC screening program
ECH Breekveldt, E Toes‐Zoutendijk… - … Journal of Cancer, 2023 - Wiley Online Library
The interval colorectal cancer (CRC) rate after negative fecal immunochemical testing (FIT)
is an important quality indicator of CRC screening programs. We analyzed the outcomes of …
is an important quality indicator of CRC screening programs. We analyzed the outcomes of …
Test, episode, and programme sensitivities of screening for colorectal cancer as a public health policy in Finland: experimental design
N Malila, T Oivanen, O Malminiemi, M Hakama - Bmj, 2008 - bmj.com
Objectives To report the sensitivities of the faecal occult blood test, screening episode, and
screening programme for colorectal cancer and the benefits of applying a randomised …
screening programme for colorectal cancer and the benefits of applying a randomised …